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Molecular Mechanisms, Diagnostic Aspects and Therapeutic Opportunities of Micro Ribonucleic Acids in Atrial Fibrillation

Journal

Publisher

MDPI
DOI: 10.3390/ijms21082742

Keywords

microRNA; atrial fibrillation; pathophysiology; biomarkers; treatment targets

Funding

  1. Ministry of Education, Science, Research and Sport of the Slovak Republic [VEGA 1/0338/17]
  2. Pfizer
  3. Research and Development Operational Program - ERDF [ITMS 26240220086]

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Micro ribonucleic acids (miRNAs) are short non-coding RNA molecules responsible for regulation of gene expression. They are involved in many pathophysiological processes of a wide spectrum of diseases. Recent studies showed their involvement in atrial fibrillation. They seem to become potential screening biomarkers for atrial fibrillation and even treatment targets for this arrhythmia. The aim of this review article was to summarize the latest knowledge about miRNA and their molecular relation to the pathophysiology, diagnosis and treatment of atrial fibrillation.

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