Journal
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
Volume 59, Issue 20, Pages 9666-9678Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.iecr.9b07076
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Funding
- Support Program of Sichuan University-Luzhou City [2017CDLZ-S02]
- Fundamental Research Funds for the Central Universities and Support Program of Chengdu Science and Technology Bureau [2019GH02-00001-HZ]
- National Natural Science Foundation of China [81570841]
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Bacterial contamination of cotton dressing can potentially cause wound infection. To solve this problem, stable and uniform decoration of silver nanoparticles (AgNPs) onto cotton fabrics is a promising strategy to endow antibacterial activity to prevent wound infection. Herein, a facile codeposition of polydopamine (PDA)/polyethyleneimine (PEI) was performed on cotton fabrics for uniformly cross-linking gallic acid (GA)-stabilized silver nanoparticles (GA@AgNPs) via Michael addition and hydrogen bonding interactions. The as-prepared GA@AgNPs/PDA-PEI-coated cotton fabrics possessed a negatively charged surface because of the high-density GA on AgNPs, showing low cytotoxicity, hemocompatibility, and hemostatic ability. Because of its stable, uniform, and anionic interface composed of GA@AgNPs, this GA@AgNPs/PDA-PEI coating could effectively resist bacterial adhesion by electrostatic repulsion and also kill the attached bacteria through sustained Ag+ release, exhibiting strong, broad-spectrum, and durable antibacterial activities toward bacteria. Therefore, these GA@AgNPs/PDA-PEI-coated cotton fabrics show great potential for clinical application as antibacterial wound dressings.
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