Related references
Note: Only part of the references are listed.Modeling Cell-Cell Interactions in Parkinson's Disease Using Human Stem Cell-Based Models
Katrin Simmnacher et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2020)
Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene
Margarita Chumarina et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease
Annika Sommer et al.
CELL STEM CELL (2018)
α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies
Iryna Prots et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
On Cell Loss and Selective Vulnerability of Neuronal Populations in Parkinson's Disease
Nicolas Giguere et al.
FRONTIERS IN NEUROLOGY (2018)
Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium
Bernt Popp et al.
SCIENTIFIC REPORTS (2018)
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model
Tetsuhiro Kikuchi et al.
NATURE (2017)
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease
Lena F. Burbulla et al.
SCIENCE (2017)
Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule
Shi-Ying Cao et al.
SCIENTIFIC REPORTS (2017)
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease
Wolfgang Wrasidlo et al.
BRAIN (2016)
Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease
Chung-Han Hsieh et al.
CELL STEM CELL (2016)
Alpha-synuclein structure, functions, and interactions
Fatemeh Nouri Emamzadeh
JOURNAL OF RESEARCH IN MEDICAL SCIENCES (2016)
Autosomal dominant Parkinson's disease caused by SNCA duplications
Takuya Konno et al.
PARKINSONISM & RELATED DISORDERS (2016)
α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models
Joseph R. Mazzulli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?
Abid Oueslati
JOURNAL OF PARKINSONS DISEASE (2016)
Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation
Sun Young Chung et al.
STEM CELL REPORTS (2016)
Creation of a library of induced pluripotent stem cells from Parkinsonian patients
Staffan Holmqvist et al.
NPJ PARKINSONS DISEASE (2016)
Dopaminergic Modulation of Decision Making and Subjective Well-Being
Robb B. Rutledge et al.
JOURNAL OF NEUROSCIENCE (2015)
DOPAMINE MIDBRAIN NEURONS IN HEALTH AND PARKINSON'S DISEASE: EMERGING ROLES OF VOLTAGE-GATED CALCIUM CHANNELS AND ATP-SENSITIVE POTASSIUM CHANNELS
E. Dragicevic et al.
NEUROSCIENCE (2015)
Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells
L. M. A. Oliveira et al.
CELL DEATH & DISEASE (2015)
Sensitive western blotting for detection of endogenous Ser129-phosphorylated α-synuclein in intracellular and extracellular spaces
Asuka Sasaki et al.
SCIENTIFIC REPORTS (2015)
Mitochondrial Alterations by PARKIN in Dopaminergic Neurons Using PARK2 Patient-Specific and PARK2 Knockout Isogenic iPSC Lines
Atossa Shaltouki et al.
STEM CELL REPORTS (2015)
Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients neurons
Steven Havlicek et al.
HUMAN MOLECULAR GENETICS (2014)
The Prevalence of Parkinson's Disease: A Systematic Review and Meta-analysis
Tamara Pringsheim et al.
MOVEMENT DISORDERS (2014)
iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis
David C. Schoendorf et al.
NATURE COMMUNICATIONS (2014)
iPSC-Derived Dopamine Neurons Reveal Differences between Monozygotic Twins Discordant for Parkinson's Disease
Chris M. Woodard et al.
CELL REPORTS (2014)
A 6.4 Mb Duplication of the α-Synuclein Locus Causing Frontotemporal Dementia and Parkinsonism Phenotype-Genotype Correlations
Eleanna Kara et al.
JAMA NEUROLOGY (2014)
Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation
Daisuke Doi et al.
STEM CELL REPORTS (2014)
Lipid Peroxidation Product 4-Hydroxy-2-Nonenal Promotes Seeding-Capable Oligomer Formation and Cell-to-Cell Transfer of α-Synuclein
Eun-Jin Bae et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
α-Synuclein Oligomers Impair Neuronal Microtubule-Kinesin Interplay
Iryna Prots et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Oxidative stress-induced posttranslational modifications of alpha-synuclein: Specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity
Wei Xiang et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2013)
The many faces of alpha-synuclein: from structure and toxicity to therapeutic target
Hilal A. Lashuel et al.
NATURE REVIEWS NEUROSCIENCE (2013)
Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling
Peter Reinhardt et al.
PLOS ONE (2013)
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
Adriana Sanchez-Danes et al.
EMBO MOLECULAR MEDICINE (2012)
Specification of Midbrain Dopamine Neurons from Primate Pluripotent Stem Cells
Jiajie Xi et al.
STEM CELLS (2012)
LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
Ha Nam Nguyen et al.
CELL STEM CELL (2011)
Neuronal vulnerability in Parkinson's disease
Kay L Double
PARKINSONISM & RELATED DISORDERS (2011)
SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress
Blake Byers et al.
PLOS ONE (2011)
In vivo demonstration that α-synuclein oligomers are toxic
Beate Winner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
Michael J. Devine et al.
NATURE COMMUNICATIONS (2011)
α-Synuclein and dopamine at the crossroads of Parkinson's disease
Lara Lourenco Venda et al.
TRENDS IN NEUROSCIENCES (2010)
Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease
Tomas Gonzalez-Hernandez et al.
FRONTIERS IN NEUROANATOMY (2010)
Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
K. Ray Chaudhuri et al.
LANCET NEUROLOGY (2009)
Genomic investigation of α-synuclein multiplication and parkinsonism
Owen A. Ross et al.
ANNALS OF NEUROLOGY (2008)
Different species of α-synuclein oligomers induce calcium influx and seeding
Karin M. Danzer et al.
JOURNAL OF NEUROSCIENCE (2007)
Self-renewing and differentiating properties of cortical neural stem cells are selectively regulated by basic fibroblast growth factor (FGF) signaling via specific FGF receptors
Dragan Maric et al.
JOURNAL OF NEUROSCIENCE (2007)
Effects of nitration on the structure and aggregation of α-synuclein
VN Uversky et al.
MOLECULAR BRAIN RESEARCH (2005)
No global loss of neocortical neurons in Parkinson's disease: A quantitative stereological study
KM Pedersen et al.
MOVEMENT DISORDERS (2005)
Dopaminergic contribution to the regulation of emotional perception
P Salgado-Pineda et al.
CLINICAL NEUROPHARMACOLOGY (2005)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
BI Giasson et al.
SCIENCE (2000)
Share Paper
