Context is everything: How context shapes modulations of responses to unattended sound

The concept of perceptual inferences taking place over multiple timescales simultaneously raises questions about how the brain can balance the demands of remaining sensitive to local rarity while utilising more global longer-term predictability to modulate cortical responses. In the present study auditory evoked potentials to four presentations of the same sound sequence containing predictable structure on a local (milliseconds to seconds) and more global (many minutes) timescales were recorded. The results from 33 participants are used to demonstrate that predictions about both local (internal predictive models) and global (meta-models that define expected precisions associated with familiar internal model states) regularities are formed. The study exposes more local context-based modulations of the P1 but more global order-based modulations of the auditory evoked N2 components. The results are discussed in terms of theoretical links advocating that uncertainty at multiple timescales could lead to differential component modulations, and the importance of considering the broader learning context in auditory evoked potential studies. (C) 2020 Elsevier B.V. All rights reserved.

Automated summary

The study investigates the role of perceptual inferences across multiple timescales, finding that the brain can balance sensitivity to local rarity with global long-term predictability. Participants formed predictions about both local and global regularities, with auditory evoked potentials showing different modulations at different timescales. The results highlight the importance of considering uncertainty at multiple timescales in auditory evoked potential studies.