Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 42, Issue 9, Pages 2635-2643Publisher
WILEY
DOI: 10.1002/hed.26186
Keywords
endoscope; laryngeal cancer; meta-analysis; narrow band imaging; white light
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Funding
- Korea Health Industry Development Institute [HI14C3228]
- National Research Foundation of Korea [2018M3A9E8020856, 2019M3A9H2032424, 2019M3E5D5064110, 2018R1D1A1B07045421]
- E.N.T. Fund of the Catholic University of Korea
- Institute of Clinical Medicine Research of Bucheon St. Mary's Hospital
- National Research Foundation of Korea [2019M3E5D5064110, 2019M3A9H2032424, 2018M3A9E8020856, 2018R1D1A1B07045421] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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We evaluated the diagnostic accuracy of narrowband imaging (NBI) in terms of detecting laryngeal cancer compared to that of white light endoscopy (WLE). Two reviewers individually searched the six databases for studies published between the first record date and December 31, 2019. We recorded the numbers of true positives, true negatives, false positives, and false negatives. Quality Assessment of Diagnostic Accuracy Studies ver. 2 software was used to assess the studies. The extent of the inter-rater agreement was also measured. The diagnostic odds ratio (OR) associated with NBI was 87.463 (95% confidence interval [CI]: 46.968, 160.873). The area under the summary receiver operating characteristic curve was 0.954. NBI was more diagnostically accurate than WLE, which was associated with a diagnostic OR of 13.750. NBI affords high diagnostic accuracy, thus supporting a role for NBI in the diagnostic work-up of laryngeal cancer.
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