Related references
Note: Only part of the references are listed.Modulating TAK1 Expression Inhibits YAP and TAZ Oncogenic Functions in Pancreatic Cancer
Raffaela Santoro et al.
MOLECULAR CANCER THERAPEUTICS (2020)
Small Molecule Inhibition of GSK-3 Specifically Inhibits the Transcription of Inhibitory Co-receptor LAG-3 for Enhanced Anti-tumor Immunity
Christopher E. Rudd et al.
CELL REPORTS (2020)
Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma
Xiaosheng Wu et al.
BLOOD (2019)
Glycogen Synthase Kinase-3β Inhibition with 9-ING-41 Attenuates the Progression of Pulmonary Fibrosis
Ann Jeffers et al.
SCIENTIFIC REPORTS (2019)
Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response
Li Ding et al.
CLINICAL CANCER RESEARCH (2019)
9-ING-41, a small-molecule glycogen synthase kinase-3 inhibitor, is active in neuroblastoma
Andrey V. Ugolkov et al.
ANTI-CANCER DRUGS (2018)
Glycogen synthase kinase 3 inhibition lowers PD-1 expression, promotes long-term survival and memory generation in antigen-specific CAR-T cells
Sadhak Sengupta et al.
CANCER LETTERS (2018)
Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling
Qingcai Meng et al.
ONCOGENE (2018)
Resibufogenin suppresses transforming growth factor-β-activated kinase 1-mediated nuclear factor-κB activity through protein kinase C-dependent inhibition of glycogen synthase kinase 3
Lu Liu et al.
CANCER SCIENCE (2018)
KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
Angelina V. Vaseva et al.
CANCER CELL (2018)
An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice
Mouad Edderkaoui et al.
GASTROENTEROLOGY (2018)
Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy
Razvan Cristescu et al.
SCIENCE (2018)
GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors
Aslamuzzaman Kazi et al.
NATURE COMMUNICATIONS (2018)
Small-Molecule Inhibition of PD-1 Transcription Is an Effective Alternative to Antibody Blockade in Cancer Therapy
Alison Taylor et al.
CANCER RESEARCH (2018)
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
Yangchun Xie et al.
GASTROENTEROLOGY (2017)
Pancreatic Ductal Adenocarcinoma: Current and Evolving Therapies
Aleksandra Adamska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Glycogen synthase kinase-3β ablation limits pancreatitis-induced acinar-to-ductal metaplasia
Li Ding et al.
JOURNAL OF PATHOLOGY (2017)
Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases
Romina Mancinelli et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
Germline mutations in pancreatic cancer and potential new therapeutic options
Rille Pihlak et al.
ONCOTARGET (2017)
Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer
Amy Walz et al.
CLINICAL CANCER RESEARCH (2017)
Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer
Nicholas J. Roberts et al.
CANCER DISCOVERY (2016)
A Metabolic Inhibitory Cocktail for Grave Cancers: Metformin, Pioglitazone and Lithium Combination in Treatment of Pancreatic Cancer and Glioblastoma Multiforme
Ilhan Elmaci et al.
BIOCHEMICAL GENETICS (2016)
Over-expression of microRNA-940 promotes cell proliferation by targeting GSK3β and sFRP1 in human pancreatic carcinoma
Hong-wei Yang et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression
Tikvah K. Hayes et al.
CANCER CELL (2016)
Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway
Qian-Qian Liu et al.
CANCER CELL INTERNATIONAL (2016)
GSK-3 inhibition overcomes chemoresistance in human breast cancer
Andrey Ugolkov et al.
CANCER LETTERS (2016)
Glycogen synthase kinase-3 is a pivotal mediator of cancer invasion and resistance to therapy
Takahiro Domoto et al.
CANCER SCIENCE (2016)
Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8+ Cytolytic T Cell Responses
Alison Taylor et al.
IMMUNITY (2016)
GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression
Sandra Baumgart et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22
Aidong Zhou et al.
NATURE CELL BIOLOGY (2016)
From bench to bedside a comprehensive review of pancreatic cancer immunotherapy
Paul R. Kunk et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2016)
GSK3β mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway
Xu Ying et al.
CANCER CELL INTERNATIONAL (2015)
MicroRNA Signaling Pathway Network in Pancreatic Ductal Adenocarcinoma
Longhao Sun et al.
JOURNAL OF GENETICS AND GENOMICS (2015)
Pancreatic cancer: from state-of-the-art treatments to promising novel therapies
Ignacio Garrido-Laguna et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2015)
Anti-tumor properties of the cGMP/protein kinase G inhibitor DT3 in pancreatic adenocarcinoma
Sabine Soltek et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2015)
Luteolin and Gemcitabine Protect Against Pancreatic Cancer in an Orthotopic Mouse Model
Jodee L. Johnson et al.
PANCREAS (2015)
Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
Eleonore Beurel et al.
PHARMACOLOGY & THERAPEUTICS (2015)
MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway
Wei Zhou et al.
Oncotarget (2015)
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib et al.
CANCER RESEARCH (2014)
miR-208-Induced Epithelial to Mesenchymal Transition of Pancreatic Cancer Cells Promotes Cell Metastasis and Invasion
Anan Liu et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2014)
Coupling G2/M arrest to the Wnt/β-catenin pathway restrains pancreatic adenocarcinoma
Sayantani Sarkar et al.
ENDOCRINE-RELATED CANCER (2014)
Inhibition of GSK-3 Induces Differentiation and Impaired Glucose Metabolism in Renal Cancer
Krishnendu Pal et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells
J-S Zhang et al.
CELL DEATH & DISEASE (2014)
GSK-3 as potential target for therapeutic irvention in cancer
James A. McCubrey et al.
ONCOTARGET (2014)
Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine
Daniel D. Von Hoff et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Aberrant Glycogen Synthase Kinase 3β Is Involved in Pancreatic Cancer Cell Invasion and Resistance to Therapy
Ayako Kitano et al.
PLOS ONE (2013)
Lithium Inhibits Tumorigenic Potential of PDA Cells through Targeting Hedgehog-GLI Signaling Pathway
Zhonglu Peng et al.
PLOS ONE (2013)
GSK-3α Promotes Oncogenic KRAS Function in Pancreatic Cancer via TAK1-TAB Stabilization and Regulation of Noncanonical NF-κB
Deepali Bang et al.
CANCER DISCOVERY (2013)
PANC-1 cells proliferative response to ionizing radiation is related to GSK-3β phosphorylation
Nora A. Mohamad et al.
BIOCHEMISTRY AND CELL BIOLOGY (2012)
ShRNA silencing glycogen synthase kinase-3 beta inhibits tumor growth and angiogenesis in pancreatic cancer
Wei Zhou et al.
CANCER LETTERS (2012)
Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms
Benoit Marchand et al.
CARCINOGENESIS (2012)
Role of TAZ as Mediator of Wnt Signaling
Luca Azzolin et al.
CELL (2012)
NF-κB as a target for pancreatic cancer therapy
Carmine Carbone et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
Dysregulation of Wnt/β-Catenin Signaling in Gastrointestinal Cancers
Bryan D. White et al.
GASTROENTEROLOGY (2012)
Presence of Somatic Mutations in Most Early-Stage Pancreatic Intraepithelial Neoplasia
Mitsuro Kanda et al.
GASTROENTEROLOGY (2012)
Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
Jeremy S. Logue et al.
GENES & DEVELOPMENT (2012)
Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine
Takeo Shimasaki et al.
JOURNAL OF GASTROENTEROLOGY (2012)
Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation
Lina Tsaadon Alon et al.
FEBS LETTERS (2011)
Disruption of a Nuclear NFATc2 Protein Stabilization Loop Confers Breast and Pancreatic Cancer Growth Suppression by Zoledronic Acid
Shiv K. Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer
J-S Zhang et al.
ONCOGENE (2011)
Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation
Sejeong Shin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
GSK-3: functional insights from cell biology and animal models
Oksana Kaidanovich-Beilin et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2011)
GSK3: a multifaceted kinase in Wnt signaling
Dianqing Wu et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
John P. Morris et al.
NATURE REVIEWS CANCER (2010)
Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapy
Shadi Mamaghani et al.
BMC CANCER (2009)
Deregulated GSK3β Sustains Gastrointestinal Cancer Cells Survival by Modulating Human Telomerase Reverse Transcriptase and Telomerase
Wei Mai et al.
CLINICAL CANCER RESEARCH (2009)
Future of Cancer Incidence in the United States: Burdens Upon an Aging, Changing Nation
Benjamin D. Smith et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells
Irina N. Gaisina et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive et al.
SCIENCE (2009)
Maintenance of constitutive IκB kinase activity by glycogen synthase kinase-3α/β in pancreatic cancer
Willie Wilson et al.
CANCER RESEARCH (2008)
Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells
Stefania Cannito et al.
CARCINOGENESIS (2008)
Gemcitabine resistance in pancreatic cancer: Picking the key players
Michael P. Kim et al.
CLINICAL CANCER RESEARCH (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
Systematic discovery of in vivo phosphorylation networks
Rune Linding et al.
CELL (2007)
Glycogen synthase kinase-3 beta; A new target in pancreatic cancer?
G. Garcea et al.
CURRENT CANCER DRUG TARGETS (2007)
Primers on molecular pathways -: The glycogen synthase kinase-3β
Daniel D. Billadeau
PANCREATOLOGY (2007)
Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
Richard S. Jope et al.
NEUROCHEMICAL RESEARCH (2007)
Aberrant nuclear accumulation of glycogen synthase kinase-3β in human pancreatic cancer:: Association with kinase activity and tumor dedifferentiation
Andrei V. Ougolkov et al.
CLINICAL CANCER RESEARCH (2006)
Glycogen synthase kinase-3β participates in nuclear factor κB-mediated gene transcription and cell survival in pancreatic cancer cells
AV Ougolkov et al.
CANCER RESEARCH (2005)
MicroRNAs: Genomics, biogenesis, mechanism, and function
DP Bartel
CELL (2004)
GSK-3: tricks of the trade for a multi-tasking kinase
BW Doble et al.
JOURNAL OF CELL SCIENCE (2003)
The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
CA Grimes et al.
PROGRESS IN NEUROBIOLOGY (2001)
Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc
JW Neal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3β in cellular and animal models of neuronal degeneration
RV Bhat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
KP Hoeflich et al.
NATURE (2000)
Share Paper
