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Resistance of mtDNA-depleted cell to apopitosis
Roberta Ferraresi et al.
CYTOMETRY PART A (2008)
Depletion of mitochondrial DNA up-regulates the expression of MDR1 gene via an increase in mRNA stability
Wan Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2008)
Hormesis and disease resistance: activation of cellular stress response pathways
Mark P. Mattson
HUMAN & EXPERIMENTAL TOXICOLOGY (2008)
Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA
Philippe A. Parone et al.
PLOS ONE (2008)
Mitochondria in cancer cells: what is so special about them?
Vladimir Gogvadze et al.
TRENDS IN CELL BIOLOGY (2008)
Induction of acquired resistance to antiestrogen by reversible mitochondrial DNA depletion in breast cancer cell line
Akihiro Naito et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Hsp60 regulation of tumor cell apoptosis
Jagadish C. Ghosh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
ER stress triggers apoptosis by activating BH3-only protein Bim
Hamsa Puthalakath et al.
CELL (2007)
The dsRNA protein kinase PKR:: Virus and cell control
M. A. Garcia et al.
BIOCHIMIE (2007)
Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion
Hsin-Chen Lee et al.
MITOCHONDRION (2007)
Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients
Man Yu et al.
IUBMB LIFE (2007)
Altered sirtuin expression is associated with node-positive breast cancer
N. Ashraf et al.
BRITISH JOURNAL OF CANCER (2006)
Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs
S. Ohta
ONCOGENE (2006)
Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer
LM Tseng et al.
GENES CHROMOSOMES & CANCER (2006)
Correlation between copy number of mitochondrial DNA and clinico-pathologic parameters of hepatocellular carcinoma
S Yamada et al.
EJSO (2006)
Mitochondrial DNA determines androgen dependence in prostate cancer cell lines
M Higuchi et al.
ONCOGENE (2006)
Coping with stress: eIF2 kinases and translational control
RC Wek et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2006)
Increased risk of cancer in patients with fumarate hydratase germline mutation
H. J. Lehtonen et al.
JOURNAL OF MEDICAL GENETICS (2006)
Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death
W Qian et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Characterization of 954 bovine full-CDS cDNA sequences
GP Harhay et al.
BMC GENOMICS (2005)
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
MX Bi et al.
EMBO JOURNAL (2005)
Mitochondrial energy metabolism is markedly impaired by D-2-hydroxyglutaric acid in rat tissues
A Latini et al.
MOLECULAR GENETICS AND METABOLISM (2005)
Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer
CW Wu et al.
GENES CHROMOSOMES & CANCER (2005)
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
JS Isaacs et al.
CANCER CELL (2005)
Mitochondria-to-nucleus stress signaling in mammalian cells: Nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis
G Biswas et al.
GENE (2005)
The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: A quantitative study using laser-captured microdissected tissues
Y Wang et al.
GYNECOLOGIC ONCOLOGY (2005)
Fumarate hydratase mutations and predisposition to cutaneous leiomyomas, uterine leiomyomas and renal cancer
NA Alam et al.
BRITISH JOURNAL OF DERMATOLOGY (2005)
Clinical value of mitochondrial mutations in colorectal cancer
A Lièvre et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance
YK Shin et al.
CANCER RESEARCH (2005)
Phosphorylation of the α-subunit of the eukaryotic initiation factor-2 (eIF2α) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition
HY Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis
Y Shidara et al.
CANCER RESEARCH (2005)
mtDNA mutations increase tumorigenicity in prostate cancer
JA Petros et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
GCN2 phosphorylation of eIF2α activates NF-κB in response to UV irradiation
HY Jiang et al.
BIOCHEMICAL JOURNAL (2005)
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
RK Jain
SCIENCE (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
Mitochondrial signaling: The retrograde response
RA Butow et al.
MOLECULAR CELL (2004)
Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma
HC Lee et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2004)
Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells
K Ameri et al.
BLOOD (2004)
Resistance of mitochondrial DNA-depleted cells against cell death - Role of mitochondrial superoxide dismutase
SY Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Large-scale mitochondrial DNA deletion mutations and nuclear genome instability in human breast cancer
WZ Zhu et al.
CANCER DETECTION AND PREVENTION (2004)
Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications
JS Carew et al.
LEUKEMIA (2003)
Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p
ZC Liu et al.
MOLECULAR CELL (2003)
Mutations in the Fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America
JR Toro et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
Humanin peptide suppresses apoptosis by interfering with Bax activation
B Guo et al.
NATURE (2003)
Mitochondria to nucleus stress signaling:: a distinctive mechanism of NFκB/Rel activation through calcineurin-mediated inactivation of IκBβ
G Biswas et al.
JOURNAL OF CELL BIOLOGY (2003)
Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum
JB Welsh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer's disease and target for cancer therapy
V Maximov et al.
MEDICAL HYPOTHESES (2002)
Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
G Arnuthan et al.
ONCOGENE (2002)
Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?
PF Chinnery et al.
LANCET (2002)
A mitochondrial specific stress response in mammalian cells
Q Zhao et al.
EMBO JOURNAL (2002)
NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in D-2-hydroxyglutaric aciduria
S Kölker et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2002)
CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
T Arnould et al.
EMBO JOURNAL (2002)
Heme-regulated eIF2α kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency
AP Han et al.
EMBO JOURNAL (2001)
Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma
V Máximo et al.
GENES CHROMOSOMES & CANCER (2001)
Accumulation of mitochondrial DNA deletions in human oral tissues - effects of betel quid chewing and oral cancer
HC Lee et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2001)
The oxidative phosphorylation (OXPHOS) system: nuclear genes and human genetic diseases
L van den Heuvel et al.
BIOESSAYS (2001)
A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ
Y Hashimoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p
T Sekito et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
MS Fliss et al.
SCIENCE (2000)
Mitochondrial role in life and death of the cell
HC Lee et al.
JOURNAL OF BIOMEDICAL SCIENCE (2000)