Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2020, Issue 14, Pages 2116-2129Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.202000178
Keywords
Aza-Diels-Alder Reactions; Quinolinium Salts; Synthesis design; Reaction mechanisms; Energy Decomposition Analysis (Eda)
Categories
Funding
- Ministry of Science and Technology of the Republic of China [MOST 105-2633-M-007-003, 107-2113-M-006-008-MY2]
Ask authors/readers for more resources
Secondary anilines were first utilized in the four-component coupling of aniline, aldehyde, alkyne, and acid to synthesize a variety of N-substituted quinolinium salts. This method was carried out under mild reaction conditions and exhibited excellent chemo- and regioselectivities. DFT calculation was performed to analyze the cyclization step, where the interaction/distortion model provided better insight into the singular selectivity of terminal/internal alkynes in reaction.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available