Journal
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
Volume 27, Issue 16, Pages 19502-19509Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s11356-020-07899-x
Keywords
Airborne endotoxin; Bacterial bioaerosol; Fungal bioaerosols; Asthma; Allergy; Children
Categories
Funding
- Department of Health, Kaohsiung City Government, Republic of China (Taiwan) [980105, 980105-1, 100C007]
- Ministry of Science and Technology, Republic of China (Taiwan) [105-2314-B-037-020, 106-2314-B-037-067]
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To evaluate the association between the presence of asthma and allergy, and airborne endotoxin in homes of school-age children in Kaohsiung City, Taiwan, with a case-control study design by matching the age and class exposure. Data collection of home visits included an interviewer-administered questionnaire and air sampling of participants' homes for endotoxin, bacteria, and fungi, as well as temperature and relative humidity measurements. Endotoxin was detected in all air samples with a median value of 0.67 EU m(-3). In the adjusted logistic regression model, household airborne endotoxin was associated with higher prevalence of asthma and allergy; OR = 4.88 (95% CI 1.16-20.55) for Q3 (between 0.67 and 1.97 EU m (-3)) vs. Q1 (< 0.31 EU m (-3)), with statistical significance. Airborne fungi were associated with higher prevalence of asthma and allergy; OR = 4.47 (95% CI 1.13-17.69) for Q3 (between 314 and 699 CFU m (-3)) vs. Q1 (< 159 CFU m (-3)) in adjusted logistic regression models. Airborne endotoxin and fungi were significantly associated with children's asthma and allergy.
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