Journal
ENVIRONMENTAL POLLUTION
Volume 259, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2019.113765
Keywords
Climate change; Bioactivity; Marine algae; Natural acidification; Marine drugs
Categories
Funding
- SZN
- Flagship RITMARE - The Italian Research for the Sea
- Deanship of Scientific Research at King Saud University [RGP-205]
- Flemish Science Foundation (FWO) [12U8918N]
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We utilized volcanic CO2 vents at Castello Aragonese off Ischia Island as a natural laboratory to investigate the effect of lowered pH/elevated CO2 on the bioactivities of extracts from fleshy brown algae Sargassum vulgare C. Agardh. We analysed the carbohydrate levels, antioxidant capacity, antibacterial, antifungal, antiprotozoal, anticancer properties and antimutagenic potential of the algae growing at the acidified site (pH similar to 6.7) and those of algae growing at the nearby control site Lacco Ameno (pH similar to 8.1). The results of the present study show that the levels of polysaccharides fucoidan and alginate were higher in the algal population at acidified site. In general, extracts for the algal population from the acidified site showed a higher antioxidant capacity, antilipidperoxidation, antibacterial, antifungal, antiprotozoal, anticancer activities and antimutagenic potential compared to the control population. The increased bioactivity in acidified population could be due to elevated levels of bioactive compounds of algae and/or associated microbial communities. In this snapshot study, we performed bioactivity assays but did not characterize the chemistry and source of presumptive bioactive compounds. Nevertheless, the observed improvement in the medicinal properties of S. vulgare in the acidified oceans provides a promising basis for future marine drug discovery. (C) 2019 Elsevier Ltd. All rights reserved.
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