Related references
Note: Only part of the references are listed.Molecular mechanisms regulating NLRP3 inflammasome activation
Eun-Kyeong Jo et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2016)
A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation
Jonathan L. Schmid-Burgk et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
Qing Zhou et al.
NATURE GENETICS (2016)
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
Hexin Shi et al.
NATURE IMMUNOLOGY (2016)
Specificity and disease in the ubiquitin system
Viduth K. Chaugule et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
Zhenyu Zhong et al.
CELL (2016)
The kinase activity of PKR represses inflammasome activity
Howard C. H. Yim et al.
CELL RESEARCH (2016)
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Yuan He et al.
NATURE (2016)
E3 ubiquitin ligases as novel targets for inflammatory diseases
Santosh Kumar Goru et al.
PHARMACOLOGICAL RESEARCH (2016)
Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis
Ismail Sergin et al.
SCIENCE SIGNALING (2016)
The Ball and Chain of Polyubiquitin Structures
Caterina Alfano et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP
Mausita Karmakar et al.
NATURE COMMUNICATIONS (2016)
p58IPK suppresses NLRP3 inflammasome activation and IL-1β production via inhibition of PKR in macrophages
Evgenii Boriushkin et al.
SCIENTIFIC REPORTS (2016)
Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis
Ismail Sergin et al.
SCIENCE SIGNALING (2016)
Converging roles of caspases in inflammasome activation, cell death and innate immunity
Si Ming Man et al.
NATURE REVIEWS IMMUNOLOGY (2016)
The Inflammasomes and Autoinflammatory Syndromes
Lori Broderick et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 (2015)
Ginsenoside Rg3 regulates S-nitrosylation of the NLRP3 inflammasome via suppression of iNOS
Sung-Jin Yoon et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome
Yiqing Yan et al.
CELL (2015)
Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
Ruth Wassermann et al.
CELL HOST & MICROBE (2015)
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Wan-ting He et al.
CELL RESEARCH (2015)
A20 Restricts Ubiquitination of Pro-Interleukin-1β Protein Complexes and Suppresses NLRP3 Inflammasome Activity
Bao H. Duong et al.
IMMUNITY (2015)
Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase
SeungHye Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse
Carlo Marchetti et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2015)
MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3
Kai Guan et al.
JOURNAL OF IMMUNOLOGY (2015)
cGAS and Ifi204 Cooperate To Produce Type I IFNs in Response to Francisella Infection
Kelly M. Storek et al.
JOURNAL OF IMMUNOLOGY (2015)
Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux
Mausita Karmakar et al.
JOURNAL OF IMMUNOLOGY (2015)
Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization
Ying-Cing Lin et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2015)
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
Ingrid E. Wertz et al.
NATURE (2015)
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki et al.
NATURE (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
Inflammasomes: mechanism of action, role in disease, and therapeutics
Haitao Guo et al.
NATURE MEDICINE (2015)
Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5
Magdalena Matusiak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection
Megan H. Orzalli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization
Liman Zhang et al.
SCIENCE (2015)
Structural and biochemical basis for induced self-propagation of NLRC4
Zehan Hu et al.
SCIENCE (2015)
Mechanisms of inflammasome activation: recent advances and novel insights
Sivapriya K. Vanaja et al.
TRENDS IN CELL BIOLOGY (2015)
The demographics of the ubiquitin system
Michael J. Clague et al.
TRENDS IN CELL BIOLOGY (2015)
Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury
Minako Ito et al.
NATURE COMMUNICATIONS (2015)
Reciprocal Regulation between Enterovirus 71 and the NLRP3 Inflammasome
Hongbin Wang et al.
CELL REPORTS (2015)
The Recombinant BCG ΔureC::hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation
Hiroyuki Saiga et al.
JOURNAL OF INFECTIOUS DISEASES (2015)
Ubiquitin-binding domains: Mechanisms of ubiquitin recognition and use as tools to investigate ubiquitin-modified proteomes
Daniel Scott et al.
PROTEOMICS (2015)
Inflammasomes and Metabolic Disease
Jorge Henao-Mejia et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 76 (2014)
NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion
Marta Wlodarska et al.
CELL (2014)
Mechanisms and Functions of Inflammasomes
Mohamed Lamkanfi et al.
CELL (2014)
Innate signaling in the inflammatory immune disorders
Cheng Qian et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2014)
Ubiquitin in the immune system
Julia Zinngrebe et al.
EMBO REPORTS (2014)
3,4-Methylenedioxy-β-nitrostyrene Inhibits NLRP3 Inflammasome Activation by Blocking Assembly of the Inflammasome
Yuan He et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
Mary A. Rodgers et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
An inherited mutation in NLRC4 causes autoinflammation in human and mice
Akiko Kitamura et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function
Mohammed G. Ghonime et al.
JOURNAL OF IMMUNOLOGY (2014)
Inflammasornes and Metabolic Disorders: Old Genes in Modern Diseases
Gregory R. Robbins et al.
MOLECULAR CELL (2014)
Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
Katrin D. Mayer-Barber et al.
NATURE (2014)
Inefficient star formation in extremely metal poor galaxies
Yong Shi et al.
NATURE (2014)
Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation
Neil Romberg et al.
NATURE GENETICS (2014)
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
Scott W. Canna et al.
NATURE GENETICS (2014)
Inflammasome: Cancer's friend or foe?
Michela Terlizzi et al.
PHARMACOLOGY & THERAPEUTICS (2014)
HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation
Maria Kalamvoki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV
Kathryn M. Monroe et al.
SCIENCE (2014)
ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS Toxin Regulates Inflammasome Activity
Santanu Bose et al.
MBIO (2014)
Inflammasomes
Marcel R. de Zoete et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
Nina Van Opdenbosch et al.
NATURE COMMUNICATIONS (2014)
IKKα negatively regulates ASC-dependent inflammasome activation
Bradley N. Martin et al.
NATURE COMMUNICATIONS (2014)
The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge
Kaiwen W. Chen et al.
CELL REPORTS (2014)
XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation
Monica Yabal et al.
CELL REPORTS (2014)
Update on enterovirus 71 infection
Peng-Nien Huang et al.
CURRENT OPINION IN VIROLOGY (2014)
Shigella Type III Secretion Protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation Independently of Pkcδ
Shiho Suzuki et al.
PLOS PATHOGENS (2014)
Inflammasomes in cancer: a double-edged sword
Ryan Kolb et al.
PROTEIN & CELL (2014)
The Pivotal Role of IKKα in the Development of Spontaneous Lung Squamous Cell Carcinomas
Zuoxiang Xiao et al.
CANCER CELL (2013)
The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation
Naeha Subramanian et al.
CELL (2013)
When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling
Lan K. Nguyen et al.
CELL COMMUNICATION AND SIGNALING (2013)
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
Kairui Mao et al.
CELL RESEARCH (2013)
The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages
Yuan He et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Human astrocytes express a novel NLRP2 inflammasome
Julia Minkiewicz et al.
GLIA (2013)
Deubiquitinases Regulate the Activity of Caspase-1 and Interleukin-1β Secretion via Assembly of the Inflammasome
Gloria Lopez-Castejon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice
Ning Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome
Teresa Fernandes-Alnemri et al.
JOURNAL OF IMMUNOLOGY (2013)
The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity
Sangjun Park et al.
JOURNAL OF IMMUNOLOGY (2013)
Cutting Edge: Mycobacterium tuberculosis but Not Nonvirulent Mycobacteria Inhibits IFN-β and AIM2 Inflammasome-Dependent IL-1β Production via Its ESX-1 Secretion System
Swati Shah et al.
JOURNAL OF IMMUNOLOGY (2013)
Cutting Edge: Mouse NAIP1 Detects the Type III Secretion System Needle Protein
Manira Rayamajhi et al.
JOURNAL OF IMMUNOLOGY (2013)
Cleavage of Interferon Regulatory Factor 7 by Enterovirus 71 3C Suppresses Cellular Responses
Xiaobo Lei et al.
JOURNAL OF VIROLOGY (2013)
The Viral Ubiquitin Ligase ICP0 Is neither Sufficient nor Necessary for Degradation of the Cellular DNA Sensor IFI16 during Herpes Simplex Virus 1 Infection
Delphine Cuchet-Lourenco et al.
JOURNAL OF VIROLOGY (2013)
Constitutive Interferon-Inducible Protein 16-Inflammasome Activation during Epstein-Barr Virus Latency I, II, and III in B and Epithelial Cells
Mairaj Ahmed Ansari et al.
JOURNAL OF VIROLOGY (2013)
Herpes Simplex Virus 1 Infection Induces Activation and Subsequent Inhibition of the IFI16 and NLRP3 Inflammasomes
Karen E. Johnson et al.
JOURNAL OF VIROLOGY (2013)
Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity
Benedicte F. Py et al.
MOLECULAR CELL (2013)
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
Erik C. Hett et al.
NATURE CHEMICAL BIOLOGY (2013)
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1 beta
Bibhuti B. Mishra et al.
NATURE IMMUNOLOGY (2013)
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
Hideki Hara et al.
NATURE IMMUNOLOGY (2013)
Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania
Djalma S. Lima-Junior et al.
NATURE MEDICINE (2013)
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
Martin R. Jakobsen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation
Jieling Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun et al.
SCIENCE (2013)
Crystal Structure of NLRC4 Reveals Its Autoinhibition Mechanism
Zehan Hu et al.
SCIENCE (2013)
Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
Jon A. Hagar et al.
SCIENCE (2013)
Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
Nobuhiko Kayagaki et al.
SCIENCE (2013)
Enterovirus 71 Protease 2Apro Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses
Bei Wang et al.
PLOS PATHOGENS (2013)
Direct Proteolytic Cleavage of NLRP1B Is Necessary and Sufficient for Inflammasome Activation by Anthrax Lethal Factor
Joseph Chavarria-Smith et al.
PLOS PATHOGENS (2013)
Mycobacterium tuberculosis and the host cell inflannmasome: a complex relationship
Volker Briken et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2013)
Activation and regulation of the inflammasomes
Eicke Latz et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Mycoplasma pneumoniae CARDS Toxin Induces Pulmonary Eosinophilic and Lymphocytic Inflammation
Jorge L. Medina et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions
Koraljka Husnjak et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis
Anca Dorhoi et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
The NLRP12 Inflammasome Recognizes Yersinia pestis
Gregory I. Vladimer et al.
IMMUNITY (2012)
An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
Sonal Khare et al.
IMMUNITY (2012)
Regulation of NF-κB by deubiquitinases
Edward W. Harhaj et al.
IMMUNOLOGICAL REVIEWS (2012)
Critical role of AIM2 in Mycobacterium tuberculosis infection
Hiroyuki Saiga et al.
INTERNATIONAL IMMUNOLOGY (2012)
Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
Christine Juliana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Conserved N- and C-terminal Regions of Flagellin
Els F. Halff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome
Eduardo Hernandez-Cuellar et al.
JOURNAL OF IMMUNOLOGY (2012)
Engineering and Structural Characterization of a Linear Polyubiquitin-Specific Antibody
Marissa L. Matsumoto et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Rune Busk Damgaard et al.
MOLECULAR CELL (2012)
Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: Regulation of subcellular localization
Sudhakar Veeranki et al.
MOLECULAR IMMUNOLOGY (2012)
Phosphorylation of NLRC4 is critical for inflammasome activation
Yan Qu et al.
NATURE (2012)
Novel role of PKR in inflammasome activation and HMGB1 release
Ben Lu et al.
NATURE (2012)
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Chong-Shan Shi et al.
NATURE IMMUNOLOGY (2012)
Activation of an NLRP3 Inflammasome Restricts Mycobacterium kansasii Infection
Chang-Chieh Chen et al.
PLOS ONE (2012)
Anthrax Lethal Factor Cleaves Mouse Nlrp1b in Both Toxin-Sensitive and Toxin-Resistant Macrophages
Kristina A. Hellmich et al.
PLOS ONE (2012)
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein
Megan H. Orzalli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Orchestrating Inflammasomes
Luigi Franchi et al.
SCIENCE (2012)
Allosteric post-translational modification codes
Ruth Nussinov et al.
TRENDS IN BIOCHEMICAL SCIENCES (2012)
Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome
Jonathan L. Levinsohn et al.
PLOS PATHOGENS (2012)
The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling
Peter Vandenabeele et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Tumor suppressor death-associated protein kinase is required for full IL-1β production
Ya-Ting Chuang et al.
BLOOD (2011)
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
Eran Elinav et al.
CELL (2011)
IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
Nagaraj Kerur et al.
CELL HOST & MICROBE (2011)
Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis
Ka-Wing Wong et al.
CELLULAR MICROBIOLOGY (2011)
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
Greta Guarda et al.
IMMUNITY (2011)
Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection
Katrin D. Mayer-Barber et al.
IMMUNITY (2011)
The PYHIN protein family as mediators of host defenses
Stefan A. Schattgen et al.
IMMUNOLOGICAL REVIEWS (2011)
MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP
Lei Jin et al.
JOURNAL OF IMMUNOLOGY (2011)
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
Eric M. Kofoed et al.
NATURE (2011)
NLR functions in plant and animal immune systems: so far and yet so close
Takaki Maekawa et al.
NATURE IMMUNOLOGY (2011)
Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database
George A. Khoury et al.
SCIENTIFIC REPORTS (2011)
Interaction with Sug1 enables Ipat ubiquitination leading to caspase 8 activation and cell death
Yatender Kumar et al.
BIOCHEMICAL JOURNAL (2010)
Chemical probing reveals insights into the signaling mechanism of inflammasome activation
Yi-Nan Gong et al.
CELL RESEARCH (2010)
Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
Bibhuti B. Mishra et al.
CELLULAR MICROBIOLOGY (2010)
Ubiquitin Makes Its Mark on Immune Regulation
Barbara A. Malynn et al.
IMMUNITY (2010)
A Novel Pathway for Inducible Nitric-oxide Synthase Activation through Inflammasomes
Carina L. Buzzo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cutting Edge: Caspase-1 Independent IL-1β Production Is Critical for Host Resistance to Mycobacterium tuberculosis and Does Not Require TLR Signaling In Vivo
Katrin D. Mayer-Barber et al.
JOURNAL OF IMMUNOLOGY (2010)
IFI16 is an innate immune sensor for intracellular DNA
Leonie Unterholzner et al.
NATURE IMMUNOLOGY (2010)
Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase
Najwane Said-Sadier et al.
PLOS ONE (2010)
Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1
Erin McElvania TeKippe et al.
PLOS ONE (2010)
Host-Detrimental Role of Esx-1-Mediated Inflammasome Activation in Mycobacterial Infection
Fredric Carlsson et al.
PLOS PATHOGENS (2010)
Pathogen recognition in the innate immune response
Himanshu Kumar et al.
BIOCHEMICAL JOURNAL (2009)
K63-specific deubiquitination by two JAMM/MPN plus complexes: BRISC-associated Brcc36 and proteasomal Poh1
Eric M. Cooper et al.
EMBO JOURNAL (2009)
Restriction of Legionella pneumophila Replication in Macrophages Requires Concerted Action of the Transcriptional Regulators Irf1 and Irf8 and Nod-Like Receptors Naip5 and Nlrc4
Anne Fortier et al.
INFECTION AND IMMUNITY (2009)
Expression of Nlrp1b Inflammasome Components in Human Fibroblasts Confers Susceptibility to Anthrax Lethal Toxin
Kuo-Chieh Liao et al.
INFECTION AND IMMUNITY (2009)
The RD1 Locus in the Mycobacterium tuberculosis Genome Contributes to Activation of Caspase-1 via Induction of Potassium Ion Efflux in Infected Macrophages
Takeshi Kurenuma et al.
INFECTION AND IMMUNITY (2009)
Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila
Christopher L. Case et al.
INFECTION AND IMMUNITY (2009)
A20: Central Gatekeeper in Inflammation and Immunity
Beatrice Coornaert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
Calcium-Independent Phospholipase A(2)beta Is Dispensable in Inflammasome Activation and Its Inhibition by Bromoenol Lactone
Luigi Franchi et al.
JOURNAL OF INNATE IMMUNITY (2009)
The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis
Laura O'Regan et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Teresa Fernandes-Alnemri et al.
NATURE (2009)
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
Veit Hornung et al.
NATURE (2009)
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
Olaf Gross et al.
NATURE (2009)
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
Tilmann Buerckstuemmer et al.
NATURE IMMUNOLOGY (2009)
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
Wenxiang Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA
Tara L. Roberts et al.
SCIENCE (2009)
Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
Marina Tiemi Shio et al.
PLOS PATHOGENS (2009)
Mycobacterium tuberculosis prevents inflammasome activation
Sharon S. Master et al.
CELL HOST & MICROBE (2008)
ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection
Ingrid C. Koo et al.
CELLULAR MICROBIOLOGY (2008)
The NLR gene family: A standard nomenclature
Jenny P. -Y. Ting et al.
IMMUNITY (2008)
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong et al.
IMMUNITY (2008)
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa et al.
NATURE (2008)
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
Karla L. Lightfield et al.
NATURE IMMUNOLOGY (2008)
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
Fayyaz S. Sutterwala et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The age of crosstalk: Phosphorylation, ubiquitination, and beyond
Tony Hunter
MOLECULAR CELL (2007)
NEK7 is a centrosomal kinase critical for microtubule nucleation
Sunghwan Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
Annick Mayor et al.
NATURE IMMUNOLOGY (2007)
Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression
Nissan Yissachar et al.
FEBS LETTERS (2006)
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
Amal Amer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
Luigi Franchi et al.
NATURE IMMUNOLOGY (2006)
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
Edward A. Miao et al.
NATURE IMMUNOLOGY (2006)
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
ED Boyden et al.
NATURE GENETICS (2006)
Protein posttranslational modifications: The chemistry of proteome diversifications
CT Walsh et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
NALP3 forms an IL-lβ-Processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
L Agostini et al.
IMMUNITY (2004)
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
S Mariathasan et al.
NATURE (2004)
Mycoplasma pneumoniae and its role as a human pathogen
KB Waites et al.
CLINICAL MICROBIOLOGY REVIEWS (2004)
The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-κB and pro-caspase-1 regulation
C Stehlik et al.
BIOCHEMICAL JOURNAL (2003)
Initiation of RPS2-specified disease resistance in Arabidopsis is coupled to the AvrRpt2-directed elimination of RIN4
MJ Axtell et al.
CELL (2003)
Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance
D Mackey et al.
CELL (2003)
Ubiquitin ligase-associated protein SGT1 is required for host and nonhost disease resistance in plants
JR Peart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The inflammasome:: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
F Martinon et al.
MOLECULAR CELL (2002)
XIAP: Apoptotic brake and promising therapeutic target
M Holcik et al.
APOPTOSIS (2001)
Tripeptidyl peptidase II promotes maturation of caspase-1 in Shigella flexneri-induced macrophage apoptosis
H Hilbi et al.
INFECTION AND IMMUNITY (2000)
Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice
EG Lee et al.
SCIENCE (2000)
Share Paper
