Journal
CURRENT NEUROPHARMACOLOGY
Volume 19, Issue 1, Pages 92-96Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570159X18666200507085335
Keywords
Brain; indirect influence; neurological; SARS-COV-2; psychological; mental health; COVID-19; transmission
Categories
Funding
- National Key R&D Program of China [2016YFC1306600, 2018YFC1314700]
- National Natural Science Foundation of China [81873782]
- Natural Science Foundation of Hubei Province [2016CFB624]
- Youth Science and Technology Morning Light Program of Wuhan City [2017050304010278]
- 2018 Hubei medical research project [WJ2019F030]
- 2018 Wuhan medical research project [S201802140011]
- 2018 Wuhan Young and Middle-aged Medical Talents Program
- 2017 Hubei Provincial Party Committee Organization Department the second batch of Hubei youth elite development plan
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Apart from common respiratory symptoms, COVID-19 may also cause neurological symptoms such as acute cerebrovascular disease and muscle pain. The virus can spread through various routes, and the epidemic can also impact the mental health of the public and medical staff, highlighting the importance of psychological crisis intervention.
The pandemic novel coronavinis disease (COVID-19) has become a global concern in which the respiratory system is not the only one involved. Previous researches have presented the common clinical manifestations including respiratory symptoms (i.e., fever and cough), fatigue and myalgia. However, there is limited evidence for neurological and psychological influences of SARS-CoV-2. In this review, we discuss the common neurological manifestations of COVID-19 including acute cerebrovascular disease (i.e., cerebral hemorrhage) and muscle ache. Possible viral transmission to the nervous system may occur via circulation, an upper nasal transcribrial route and/or conjunctival route. Moreover, we cannot ignore the psychological influence on the public, medical staff and confirmed patients. Dealing with public psychological barriers and performing psychological crisis intervention are an important part of public health interventions.
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