Journal
CELL METABOLISM
Volume 23, Issue 6, Pages 1004-1012Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2016.05.013
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Funding
- Jane Coffin Childs Memorial Fund for Medical Research
- NIH [R37 AG024365]
- HHMI
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As the first and most direct process influencing the proteostasis capacity of a cell, regulation of translation influences lifespan across taxa. Here we highlight some of the newly discovered means by which translational regulation affects cellular proteostasis, with a focus on mechanisms that may ultimately impinge upon the aging process.
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