Journal
CRITICAL REVIEWS IN MICROBIOLOGY
Volume 46, Issue 2, Pages 194-212Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/1040841X.2020.1739622
Keywords
Endodontic; biofilm; eradication; prevention
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Endodontic disease, a biofilm infection of the root canal space, is a significant cause of dental morbidity worldwide. Endodontic treatment, or root canal treatment, as it is commonly known is founded on the ability to eradicate microbial biofilm infection and prevent re-infection of the highly complex root canal space. Despite many advances in clinical endodontics we have seen little improvement in outcomes. The aim of this critical review paper is to provide a contemporary view of endodontic microbiology and biofilm polymicrobiality, provide an understanding of the host response, and how together these impact upon clinical treatment. Ultimately, it is intended to provide insight into novel opportunities and strategies for the future diagnostics, treatment, and prevention of endodontic disease.
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