4.6 Article

APOBEC3A damages the cellular genome during DNA replication

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

Nicholas J. Haradhvala et al.

Article Biochemistry & Molecular Biology

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

Vladimir B. Seplyarskiy et al.

GENOME RESEARCH (2016)

Review Biochemistry & Molecular Biology

APOBEC3 genes: retroviral restriction factors to cancer drivers

Stephen Henderson et al.

TRENDS IN MOLECULAR MEDICINE (2015)

Review Virology

APOBECs and virus restriction

Reuben S. Harris et al.

VIROLOGY (2015)

Article Virology

APOBEC3A Functions as a Restriction Factor of Human Papillomavirus

Cody J. Warren et al.

JOURNAL OF VIROLOGY (2015)

Article Genetics & Heredity

Error-free versus mutagenic processing of genomic uracil-Relevance to cancer

Hans E. Krokan et al.

DNA REPAIR (2014)

Article Biochemistry & Molecular Biology

Genomic Uracil Homeostasis during Normal B Cell Maturation and Loss of This Balance during B Cell Cancer Development

Sophia Shalhout et al.

MOLECULAR AND CELLULAR BIOLOGY (2014)

Review Cell Biology

Causes and consequences of replication stress

Michelle K. Zeman et al.

NATURE CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties

Mithun Mitra et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

A Biochemical Analysis Linking APOBEC3A to Disparate HIV-1 Restriction and Skin Cancer

Phuong Pham et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Multidisciplinary Sciences

APOBEC3B is an enzymatic source of mutation in breast cancer

Michael B. Burns et al.

NATURE (2013)

Article Multidisciplinary Sciences

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence et al.

NATURE (2013)

Article Multidisciplinary Sciences

Signatures of mutational processes in human cancer

Ludmil B. Alexandrov et al.

NATURE (2013)

Article Genetics & Heredity

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

Steven A. Roberts et al.

NATURE GENETICS (2013)

Article Cell Biology

DNA Damage Sensing by the ATM and ATR Kinases

Alexandre Marechal et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Cell Biology

Base Excision Repair

Hans E. Krokan et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Biology

AID/APOBEC cytosine deaminase induces genome-wide kataegis

Artem G. Lada et al.

BIOLOGY DIRECT (2012)

Article Biochemistry & Molecular Biology

Mutational Processes Molding the Genomes of 21 Breast Cancers

Serena Nik-Zainal et al.

Article Cell Biology

APOBEC3 proteins and genomic stability The high cost of a good defense

Inigo Narvaiza et al.

CELL CYCLE (2012)

Article Biochemistry & Molecular Biology

Biochemical Analysis of Hypermutation by the Deoxycytidine Deaminase APOBEC3A

Robin P. Love et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

Steven A. Roberts et al.

MOLECULAR CELL (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Biochemistry & Molecular Biology

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

Sebastien Landry et al.

EMBO REPORTS (2011)

Review Biochemistry & Molecular Biology

The DNA Damage Response: Making It Safe to Play with Knives

Alberto Ciccia et al.

MOLECULAR CELL (2010)

Review Cell Biology

ATR: an essential regulator of genome integrity

Karlene A. Cimprich et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Multidisciplinary Sciences

Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions

Jean-Pierre Vartanian et al.

SCIENCE (2008)

Review Genetics & Heredity

The ATR pathway: Fine-tuning the fork

Renee D. Paulsen et al.

DNA REPAIR (2007)

Article Multidisciplinary Sciences

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

Kum-Joo Shin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

APOBEC3 proteins inhibit human LINE-1 retrotransposition

Heide Muckenfuss et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Biochemistry & Molecular Biology

The ATM-mediated DNA-damage response: taking shape

Yosef Shiloh

TRENDS IN BIOCHEMICAL SCIENCES (2006)

Article Multidisciplinary Sciences

Cellular inhibitors of long interspersed element 1 and Alu retrotransposition

Hal P. Bogerd et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons

H Chen et al.

CURRENT BIOLOGY (2006)

Article Biochemistry & Molecular Biology

APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells

HP Bogerd et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases

SG Conticello et al.

MOLECULAR BIOLOGY AND EVOLUTION (2005)

Article Multidisciplinary Sciences

Cell-cycle checkpoints and cancer

MB Kastan et al.

NATURE (2004)

Article Multidisciplinary Sciences

Replication protein A-mediated recruitment and activation of Rad17 complexes

L Zou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

A Sohail et al.

NUCLEIC ACIDS RESEARCH (2003)

Article Biochemistry & Molecular Biology

DNA determination mediates innate immunity to retroviral infection

RS Harris et al.

Article Immunology

Constitutive expression of AID leads to tumorigenesis

I Okazaki et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2003)

Article Multidisciplinary Sciences

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

J Chaudhuri et al.

NATURE (2003)

Article Biotechnology & Applied Microbiology

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

A Jarmuz et al.

GENOMICS (2002)

Article Biochemistry & Molecular Biology

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

H Zhao et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)

Review Multidisciplinary Sciences

The DNA damage response: putting checkpoints in perspective

BBS Zhou et al.

NATURE (2000)