Journal
CLINICAL INFECTIOUS DISEASES
Volume 71, Issue 16, Pages 2233-2235Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa408
Keywords
SARS-CoV-2; COVID-19; HIV-1; HCV; antibody
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Funding
- Shenzhen Science and Technology Research and Development Project [202002073000002]
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The effect of host immune status on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains unknown. Here, we report the first case of coronavirus disease 2019 (COVID-19) with human immunodeficiency virus type 1 (HIV-1)/hepatitis C virus coinfection, who showed a persistently negative SARS-CoV-2 RNA test but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on early SARS-CoV-2 clearance.
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