Journal
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Volume 58, Issue 7, Pages 1029-1036Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1515/cclm-2020-0502
Keywords
antibodies; anticoagulation; autopsy; coagulation parameters; COVID-19; D-dimer; disseminated intravascular coagulation; heparin; low-molecular-weight heparin; pulmonary embolism; SARS-CoV-2; thrombosis
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The timely and accurate diagnosis of infection with severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), remains the cornerstone of efforts to provide appropriated treatment for patients, to limit further spread of the virus and ultimately to eliminate the virus from the human society. We focus this article on (a) developments for improvement of diagnosis of specific SARS-CoV-2 virus, (b) laboratory changes in the immunologic and coagulation system, (c) therapeutic options for anticoagulant treatment of seriously affected patients and (d) on the perspectives through improvement of diagnostic and therapeutic medical procedures.
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