Related references
Note: Only part of the references are listed.Empagliflozin reduces myocardial ketone utilization while preserving glucose utilization in diabetic hypertensive heart disease: A hyperpolarized 13C magnetic resonance spectroscopy study
Desiree Abdurrachim et al.
DIABETES OBESITY & METABOLISM (2019)
Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency
Kim L. Ho et al.
CARDIOVASCULAR RESEARCH (2019)
Cardiovascular Effects of Treatment With the Ketone Body 3-Hydroxybutyrate in Chronic Heart Failure Patients
Roni Nielsen et al.
CIRCULATION (2019)
Heart Disease and Stroke Statistics-2019 Update A Report From the American Heart Association
Emelia J. Benjamin et al.
CIRCULATION (2019)
Sodium-glucose co-transporter 2 inhibition with empagliflozin improves cardiac function in non-diabetic rats with left ventricular dysfunction after myocardial infarction
Salva R. Yurista et al.
EUROPEAN JOURNAL OF HEART FAILURE (2019)
Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics
Carlos G. Santos-Gallego et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction
J. J. V. McMurray et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense
Julie L. Horton et al.
JCI INSIGHT (2019)
Cardiovascular Metabolomics
Robert W. McGarrah et al.
CIRCULATION RESEARCH (2018)
Pulsatile arterial haemodynamics in heart failure
Thomas Weber et al.
EUROPEAN HEART JOURNAL (2018)
Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders
Katrin Augustin et al.
LANCET NEUROLOGY (2018)
Increased Cardiac Uptake of Ketone Bodies and Free Fatty Acids in Human Heart Failure and Hypertrophic Left Ventricular Remodeling
Gabor Voros et al.
CIRCULATION-HEART FAILURE (2018)
Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis
Sara B. Seidelmann et al.
LANCET PUBLIC HEALTH (2018)
Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts
Tsung-Ming Lee et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Ketone Body Infusion With 3-Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study
Lars C. Gormsen et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)
On the Metabolism of Exogenous Ketones in Humans
Brianna J. Stubbs et al.
FRONTIERS IN PHYSIOLOGY (2017)
Cardiac-Specific Bdh1 Overexpression Ameliorates Oxidative Stress and Cardiac Remodeling in Pressure Overload-Induced Heart Failure
Motoki Uchihashi et al.
CIRCULATION-HEART FAILURE (2017)
Sodium Glucose Cotransporter-2 Inhibition in Heart Failure Potential Mechanisms, Clinical Applications, and Summary of Clinical Trials
Yuliya Lytvyn et al.
CIRCULATION (2017)
Nutritional ketone salts increase fat oxidation but impair high-intensity exercise performance in healthy adult males
Trevor O'Malley et al.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2017)
Complex Energy Metabolic Changes in Heart Failure With Preserved Ejection Fraction and Heart Failure With Reduced Ejection Fraction
Kirstie A. De Jong et al.
CANADIAN JOURNAL OF CARDIOLOGY (2017)
The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model
Michael Joubert et al.
DIABETES (2017)
Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics
Patrycja Puchalska et al.
CELL METABOLISM (2017)
Understanding the Physiology of FGF21
Ffolliott Martin Fisher et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 78 (2016)
β-Hydroxybutyrate elevation as a compensatory response against oxidative stress in cardiomyocytes
Manabu Nagao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes
Pete J. Cox et al.
CELL METABOLISM (2016)
Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure
Kenneth C. Bedi et al.
CIRCULATION (2016)
The Failing Heart Relies on Ketone Bodies as a Fuel
Gregory Aubert et al.
CIRCULATION (2016)
Insulin Signaling and Heart Failure
Shavonn C. Harper et al.
CIRCULATION RESEARCH (2016)
Assessing Cardiac Metabolism A Scientific Statement From the American Heart Association
Heinrich Taegtmeyer et al.
CIRCULATION RESEARCH (2016)
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes
Ele Ferrannini et al.
DIABETES (2016)
Effect of Empagliflozin on Left Ventricular Mass and Diastolic Function in Individuals With Diabetes: An Important Clue to the EMPA-REG OUTCOME Trial?
Subodh Verma et al.
DIABETES CARE (2016)
CV Protection in the EMPA-REG OUTCOME Trial: A Thrifty Substrate Hypothesis
Ele Ferrannini et al.
DIABETES CARE (2016)
Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation
Zhongyu Xie et al.
MOLECULAR CELL (2016)
Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure
Wynn G. Hunter et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)
MicroRNAs for Restenosis and Thrombosis After Vascular Injury
Christian Riehle et al.
CIRCULATION RESEARCH (2016)
Hyperketonemia (Acetoacetate) Upregulates NADPH Oxidase 4 and Elevates Oxidative Stress, ICAM-1, and Monocyte Adhesivity in Endothelial Cells
Preeti Kanikarla-Marie et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone
Amil M. Shah et al.
CIRCULATION (2015)
Systemic, Cerebral and Skeletal Muscle Ketone Body and Energy Metabolism During Acute Hyper-D-β-Hydroxybutyratemia in Post-Absorptive Healthy Males
Kristian H. Mikkelsen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease
Yun-Hee Youm et al.
NATURE MEDICINE (2015)
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
Caroline Bonner et al.
NATURE MEDICINE (2015)
Effects of Medium-Chain Triglycerides on Weight Loss and Body Composition: A Meta-Analysis of Randomized Controlled Trials
Karen Mumme et al.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS (2015)
Do ketogenic diets really suppress appetite? A systematic review and meta-analysis
A. A. Gibson et al.
OBESITY REVIEWS (2015)
Metabolomic Fingerprint of Heart Failure with Preserved Ejection Fraction
Beshay N. Zordoky et al.
PLOS ONE (2015)
Mechanical Unloading Promotes Myocardial Energy Recovery in Human Heart Failure
Anisha A. Gupte et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2014)
Monocarboxylate Transporter 1 Deficiency and Ketone Utilization
Peter M. van Hasselt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling
Rebecca C. Schugar et al.
MOLECULAR METABOLISM (2014)
Acute nutritional ketosis: implications for exercise performance and metabolism
Pete J. Cox et al.
EXTREME PHYSIOLOGY & MEDICINE (2014)
Perturbations in the gene regulatory pathways controlling mitochondrial energy production in the failing heart
Gregory Aubert et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload
Pavel Zhabyeyev et al.
CARDIOVASCULAR RESEARCH (2013)
Hyperpolarized 13C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart
Marie A. Schroeder et al.
EUROPEAN JOURNAL OF HEART FAILURE (2013)
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
Tadahiro Shimazu et al.
SCIENCE (2013)
Fibroblast growth factor 21 protects against cardiac hypertrophy in mice
A. Planavila et al.
NATURE COMMUNICATIONS (2013)
Exhaled Acetone as a New Biomarker of Heart Failure Severity
Fabiana G. Marcondes-Braga et al.
CHEST (2012)
Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects
Kieran Clarke et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2012)
A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects
Cameron J. Holloway et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes
Dongjuan Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
Oxidative stress and heart failure
Hiroyuki Tsutsui et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)
Ikuo Kimura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Low-carbohydrate/high-fat diet attenuates pressure overload-induced ventricular remodeling and dysfunction
Monika K. Duda et al.
JOURNAL OF CARDIAC FAILURE (2008)
High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets
Naveen Sharma et al.
JOURNAL OF HYPERTENSION (2008)
Compensated cardiac hypertrophy is characterised by a decline in palmitate oxidation
Ashwin Akki et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)
Low carbohydrate diet decreases myocardial insulin signaling and increases susceptibility to myocardial ischemia
Peipei Wang et al.
LIFE SCIENCES (2008)
Low carbohydrate ketogenic diet enhances cardiac tolerance to global ischaemia
Naji S. Al-Zaid et al.
ACTA CARDIOLOGICA (2007)
Mechanisms of disease - The failing heart - An engine out of fuel
Stefan Neubauer
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension
Isidore C. Okere et al.
HYPERTENSION (2006)
Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors - A meta-analysis of randomized controlled trials
AJ Nordmann et al.
ARCHIVES OF INTERNAL MEDICINE (2006)
(D)-β-hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G
AKP Taggart et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Uncoupling proteins in human heart
AJ Murray et al.
LANCET (2004)
Mechanisms for increased glycolysis in the hypertrophied rat heart
L Nascimben et al.
HYPERTENSION (2004)
β-hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content
WC Stanley et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts
ZT Zou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy
VG Dávila-Román et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)
Hyperketonemia increases tumor necrosis factor-α secretion in cultured U937 monocytes and type 1 diabetic patients and is apparently mediated by oxidative stress and cAMP deficiency
SK Jain et al.
DIABETES (2002)
Non-invasive measurements of myocardial carbon metabolism using in vivo 13C NMR spectroscopy
A Ziegler et al.
NMR IN BIOMEDICINE (2002)
Accelerated rates of glycolysis in the hypertrophied heart: are they a methodological artifact?
HS Leong et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Deactivation of peroxisome proliferator-activated receptor-α during cardiac hypertrophic growth
PM Barger et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Share Paper
