Journal
CHROMOSOMA
Volume 129, Issue 2, Pages 115-120Publisher
SPRINGER
DOI: 10.1007/s00412-020-00737-6
Keywords
Microcephaly; Neurodevelopment; Cell fate; Growth defects; DNA damage response; Centrosomes; Cilia; Mitosis; Differentiation; Stem cells
Funding
- Spanish Ministry of Science, Innovation and Universities [PGC2018-095616-B-I00/GINDATA]
- Spanish Ministry of Science, Innovation and Universities (FEDER)
- Centres of Excellence Severo Ochoa award
- CERCA Programme
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The International University of Andalucia (UNIA) Current Trends in Biomedicine Workshop on Molecular Causes of Primary Microcephaly and Related Diseases took place in Baeza, Spain, November 18-20, 2019. This meeting brought together scientists from Europe, the USA and China to discuss recent advances in our molecular and genetic understanding of a group of rare neurodevelopmental diseases characterised by primary microcephaly, a condition in which head circumference is smaller than normal at birth. Microcephaly can be caused by inherited mutations that affect key cellular processes, or environmental exposure to radiation or other toxins. It can also result from viral infection, as exemplified by the recent Zika virus outbreak in South America. Here we summarise a number of the scientific advances presented and topics discussed at the meeting.
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