4.6 Article

Cyanine-Like Boronic Acid-Derived Salicylidenehydrazone Complexes (Cy-BASHY) for Bioimaging Applications

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 26, Issue 62, Pages 14064-14069

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.202001623

Keywords

bioimaging; dyes; fluorescence; photochemistry; two-photon absorption

Funding

  1. Portuguese FundacAo para a Ciencia e a Tecnologia (FCT) [SFRH/BD/94779/2013, LISBOA-01-0145-FEDER-029967, PTDC/QUI-QOR/29967/2017]
  2. iMed.ULisboa [UIDB/04138/2020, UIDP/04138/2020]
  3. Spanish Ministerio de Ciencia, Innovacion y Universidades [CTQ2014-54729-C2-1-P, CTQ2017-89832-P, CTQ2016-75870-P, RD16/0006/0012, BES-2015-074458]
  4. Junta de Andalucia [P12-FQM-2140, UMA18-FEDERJA-007]
  5. Junta de Andalucia (Andalusian Board of Health) [PI0250-2016]
  6. European Regional Development Fund (ERDF)

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Boronic acid-derived salicylidenehydrazone complex (BASHY) dyes with a polymethine backbone were designed to yield efficient red-emitting and two-photon absorbing fluorophores that can be used as markers for astrocytes. The dyes are chemically stable in aqueous solution and do not undergo photodecomposition. Their photophysical properties can be electronically fine-tuned and thereby adapted to potentially different imaging situations and requirements.

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