Journal
CELL
Volume 165, Issue 2, Pages 272-275Publisher
CELL PRESS
DOI: 10.1016/j.cell.2016.03.031
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Improving efficacy of immune checkpoint blockade for cancer can be facilitated by combining these agents with each other and/or with other conventional or targeted therapies. Interferon and innate immune signaling pathways in immune and tumor cells have emerged as intriguing determinants of response and resistance, often in complex and seemingly paradoxical ways.
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