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Stem Cells: A Renaissance in Human Biology Research

Journal

CELL
Volume 165, Issue 7, Pages 1572-1585

Publisher

CELL PRESS
DOI: 10.1016/j.cell.2016.05.043

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Funding

  1. G. Harold and Leila Y. Mathers Charitable Foundation
  2. Leona M. and Harry B. Helmsley Charitable Trust [2012-PG-MED002]
  3. Moxie Foundation
  4. McKnight Foundation
  5. Universidad Catolica San Antonio de Murcia (UCAM)
  6. Fundacion Dr. Pedro Guillen

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The understanding of human biology and how it relates to that of other species represents an ancient quest. Limited access to human material, particularly during early development, has restricted researchers to only scratching the surface of this inherently challenging subject. Recent technological innovations, such as single cell omics'' and human stem cell derivation, have now greatly accelerated our ability to gain insights into uniquely human biology. The opportunities afforded to delve molecularly into scarce material and to model human embryogenesis and pathophysiological processes are leading to new insights of human development and are changing our understanding of disease and choice of therapy options.

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