4.7 Article

Unusually persistent Gαi-signaling of the neuropeptide Y2 receptor depletes cellular Gi/o pools and leads to a Gi-refractory state

Related references

Note: Only part of the references are listed.
Article Cell Biology

Different mode of arrestin-3 binding at the human Y1 and Y2 receptor

Lizzy Wanka et al.

CELLULAR SIGNALLING (2018)

Article Pharmacology & Pharmacy

G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor

Anette Kaiser et al.

MOLECULAR PHARMACOLOGY (2018)

Article Pharmacology & Pharmacy

G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

Krishna Sriram et al.

MOLECULAR PHARMACOLOGY (2018)

Article Biochemistry & Molecular Biology

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

Alex R. B. Thomsen et al.

Article Chemistry, Multidisciplinary

A cleavable cytolysin-neuropeptide Y bioconjugate enables specific drug delivery and demonstrates intracellular mode of action

Verena M. Ahrens et al.

JOURNAL OF CONTROLLED RELEASE (2015)

Article Multidisciplinary Sciences

Visualization of arrestin recruitment by a G-protein-coupled receptor

Arun K. Shukla et al.

NATURE (2014)

Review Pharmacology & Pharmacy

Opioid receptor desensitization: mechanisms and its link to tolerance

Stephane Allouche et al.

FRONTIERS IN PHARMACOLOGY (2014)

Article Neurosciences

Increased Agonist Affinity at the μ-Opioid Receptor Induced by Prolonged Agonist Exposure

William T. Birdsong et al.

JOURNAL OF NEUROSCIENCE (2013)

Review Pharmacology & Pharmacy

Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons

Vu C. Dang et al.

BRITISH JOURNAL OF PHARMACOLOGY (2012)

Review Cell Biology

Regulation of β-adrenergic receptor function An emphasis on receptor resensitization

Neelakantan T. Vasudevan et al.

CELL CYCLE (2011)

Article Chemistry, Medicinal

Long-Acting Lipidated Analogue of Human Pancreatic Polypeptide Is Slowly Released into Circulation

Kathrin Bellmann-Sickert et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

Article Chemistry, Medicinal

Incorporation of ortho-Carbaboranyl-Nε-Modified L-Lysine into Neuropeptide Y Receptor Y1- and Y2-Selective Analogues

Verena M. Ahrens et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

Article Chemistry, Multidisciplinary

Breast-Cancer Diagnosis by Neuropeptide Y Analogues: From Synthesis to Clinical Application

Irfan U. Khan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Biochemistry & Molecular Biology

Ligand-induced Internalization and Recycling of the Human Neuropeptide Y2 Receptor Is Regulated by Its Carboxyl-terminal Tail

Cornelia Walther et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Pharmacology & Pharmacy

Tolerance to the Antinociceptive Effect of Morphine in the Absence of Short-Term Presynaptic Desensitization in Rat Periaqueductal Gray Neurons

Leon W. Fyfe et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Article Biochemistry & Molecular Biology

Neuropeptide Y and its Y2 receptor: potential targets in neuroblastoma therapy

C. Lu et al.

ONCOGENE (2010)

Review Pharmacology & Pharmacy

Signaling by internalized G-protein-coupled receptors

Davide Calebiro et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Review Multidisciplinary Sciences

The structure and function of G-protein-coupled receptors

Daniel M. Rosenbaum et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

Sebastien Ferrandon et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

Florian Mullershausen et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

NPY receptors in human cancer:: A review of current knowledge

Meike Koerner et al.

PEPTIDES (2007)

Article Endocrinology & Metabolism

The human thyrotropin receptor is predominantly internalized by β-arrestin 2

Romy Frenzel et al.

ENDOCRINOLOGY (2006)

Review Pharmacology & Pharmacy

Sensitization of adenylate cyclase by Gαi/o-coupled receptors

VJ Watts et al.

PHARMACOLOGY & THERAPEUTICS (2005)

Review Biochemistry & Molecular Biology

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

David P. Siderovski et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2005)

Review Neurosciences

Desensitization of G protein-coupled receptors and neuronal functions

RR Gainetdinov et al.

ANNUAL REVIEW OF NEUROSCIENCE (2004)

Article Pharmacology & Pharmacy

Neuropeptide Y and energy homeostasis: insights from Y receptor knockout models

H Herzog

EUROPEAN JOURNAL OF PHARMACOLOGY (2003)

Review Pharmacology & Pharmacy

Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status

E Parker et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2002)

Review Pharmacology & Pharmacy

Regulation and role of adenylyl cyclase isoforms

J Hanoune et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2001)

Article Biochemistry & Molecular Biology

The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats

C Cabrele et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

Regulation and intracellular trafficking pathways of the endothelin receptors

T Bremnes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)