Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 168, Issue 6, Pages 785-788Publisher
SPRINGER
DOI: 10.1007/s10517-020-04802-z
Keywords
magnetite nanoparticles; magnetite nanospheres; chitosan; leukocytes
Categories
Ask authors/readers for more resources
Nanosized magnetite particles (magnetic nanospheres) are a prospective basis for creation of new diagnostic and therapeutic agents. The structure of blood leukocytes and the leukocytic formula are studied in adult rats over a period of 120 days after a single intravenous injection of chitosan-modified nanosized magnetite particles. No effects of chitosan-modified magnetic nanospheres on the structure of rat blood leukocytes are detected. Injection of suspension of chitosan-modified magnetite nanospheres is associated with an increase in the levels of monocytes, segmented and stab neutrophils, and a decrease in lymphocyte counts in the blood of rats. The shifts in the leukogram parameters are transitory, the picture returned to normal by day 40 postinjection.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available