Journal
BIOPROCESS AND BIOSYSTEMS ENGINEERING
Volume 43, Issue 8, Pages 1499-1508Publisher
SPRINGER
DOI: 10.1007/s00449-020-02343-3
Keywords
ZnO; Zinc oxide; Metal oxides; Mn-doped ZnO; Green synthesis; Leaf extracts; Melastoma malabathricum; Antibacterial; Antimicrobial
Funding
- Universiti Brunei Darussalam, Brunei Darussalam [UBD/RSCH/1.4/FICBF(b)/2018/012]
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Zinc oxide (ZnO) is considered as a potential antimicrobial agent. This work aims to investigate the properties of ZnO and Mn-doped ZnO (1% and 5%) fabricated using aqueous leaf extract of Melastoma malabathricum via green synthesis and its antibacterial activities. The synthesized ZnO and Mn-doped ZnO were characterized using different techniques such as powder X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy and UV-Vis diffuse reflectance spectroscopy. The synthesized ZnO and Mn-doped ZnO were tested for its antibacterial properties on two Gram-negative bacteria: Escherichia coli and Pseudomonas aeruginosa, and two Gram-positive bacteria: Bacillus subtilis and Staphylococcus aureus. The results showed positive antibacterial effects for B. subtilis and S. aureus only. Among the three materials tested, 1% Mn-doped ZnO exhibited the highest antibacterial activity for B. subtilis with the minimum inhibitory concentration being 50 mg/mL.
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