Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 124, Issue -, Pages -Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2020.109923
Keywords
Tetrahydroxystilbene; Polygonummultiflorum; Pharmacological activities; Traditional Chinese medicine
Funding
- National Natural Science Foundation general projects from China [81470432]
- Natural Science Foundation of Anhui Province [1808085MH250]
- Talent Fund of Anhui Province [2018H161]
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2,3,5,4,-Tetrahydroxystilbene 2-O-beta-D-glucoside (TSG) is the main active constituent of the traditional Chinese medicine, Polygonum multiflorum; it was discovered that the compound has various biological activities and medicinal value including anti-aging, antioxidative (via scavenging free radicals), antihypercholesterolemic, anti-atherosclerotic, anti-inflammatory, hepatoprotective, and anti-tumor effects. TSG aids in prevention and treatment of Alzheimer's disease. With its wide clinical application, its separation and purification has become a research hotspot. In this paper, the pharmacological action, extraction process, and application prospects of TSG were reviewed in order to provide references for further development of TSG.
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