Journal
BIOCHIP JOURNAL
Volume 14, Issue 1, Pages 110-123Publisher
KOREAN BIOCHIP SOCIETY-KBCS
DOI: 10.1007/s13206-019-4110-x
Keywords
Lipid membrane; Supported lipid bilayer; sensor; Lipid raft; Biochip
Funding
- Samsung Research Funding & Incubation Center of Samsung Electronics [SRFC-TE1903-01]
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Lipid membranes and their applications in analytical biochip devices represent a great tool for the study of membrane dynamics and the related biological phenomena. Lipid-membrane-assisted surface-sensitive sensors have employed to provide biological information as they improve molecular survivability as well as rule out incorrect signals arising from unwanted nonspecific binding between target molecules with sensor surfaces. To enhance the accuracy of the signal as well as the sensitivity of biochip sensors, a variety of strategies have been employed. Here, we introduce various types of in vitro model membrane platforms/techniques and discuss current challenges in the lipid-membrane-assisted surface-sensitive analytical sensors application.
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