Journal
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Volume 1873, Issue 2, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.bbcan.2020.188352
Keywords
Metastasis; Redox metabolism; Redox signaling; Tumor angiogenesis
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Funding
- Spanish Ministry of Science, Innovation and Universities [PID2019-105010RB-I00]
- Andalusian Government [UMA18FEDERJA-220]
- FEDER [UMA18FEDERJA-220]
- Plan Propio de Investigacion y Transferencia (U. Malaga)
- group BIO 267 (Andalusian Government)
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Redox reactions pervade all biology. The control of cellular redox state is essential for bioenergetics and for the proper functioning of many biological functions. This review traces a timeline of findings regarding the connections between redox and cancer. There is ample evidence of the involvement of cellular redox state on the different hallmarks of cancer. Evidence of the control of tumor angiogenesis and metastasis through modulation of cell redox state is reviewed and highlighted.
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