4.7 Article

Trendy e-cigarettes enter Europe: chemical characterization of JUUL pods and its aerosols

Journal

ARCHIVES OF TOXICOLOGY
Volume 94, Issue 6, Pages 1985-1994

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00204-020-02716-3

Keywords

JUUL; Electronic cigarette; Nicotine salt; Nicotine delivery; Vapor chemistry; Benzoic acid

Categories

Funding

  1. German Federal Institute for Risk Assessment (BfR) [1322-535]

Ask authors/readers for more resources

The popularity and the high nicotine content of the American pod e-cigarette JUUL have raised many concerns. To comply with European law, the nicotine concentration in the liquids of the European version, which has been recently released on the market, is limited to below 20 mg/mL. This limit can possibly be circumvented by technological adjustments that increase vaporization and consequently, elevate nicotine delivery. In this study, we compare vapor generation and nicotine delivery of the initial European version, a modified European version, and the original American high-nicotine variant using a machine vaping set-up. Additionally, benzoic acid and carbonyl compounds are quantified in the aerosol. Further, concentrations of nicotine, benzoic acid, propylene glycol, and glycerol, along with the density and pH value of JUUL e-liquids have been assessed. Whereas the initial European version did not compensate for the low nicotine content in the liquid, we provide evidence for an increased vaporization by the modified European version. As a consequence, nicotine delivery per puff approximates the American original. Notably, this is not associated with an increased generation of carbonyl compounds. Our data suggest a similar addictiveness of the enhanced European version and the original American product.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available