4.6 Article

Probable Molecular Mechanism of Remdesivir for the Treatment of COVID-19: Need to Know More

Journal

ARCHIVES OF MEDICAL RESEARCH
Volume 51, Issue 6, Pages 585-586

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.arcmed.2020.05.001

Keywords

SARS-CoV-2; Remdesivir; COVID-19; Therapeutic molecule

Funding

  1. Hallym University Research Fund
  2. Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education [NRF-2017R1A2B4012944]

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COVID-19 is now pandemic throughout the world. Scientist, doctors are searching for effective therapy of this diseases. The remdesivir, an antiviral drug, is appeared as 'molecule of hope' for the treatment of this disease. USFDA gave emergency approval to this drug for the treatment of COVID-19. The molecular mechanism is unknown. In this pa per, we tried to describe the probable molecular mechanism of remdesivir to inhibit the RNA synthesis of SARS-CoV-2. However, more detail mechanism is needed to understand mechanism of action of remdesivir. (c) 2020 IMSS. Published by Elsevier Inc.

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