Journal
APPLIED PHYSICS LETTERS
Volume 116, Issue 15, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/5.0006248
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Funding
- National Natural Science Foundation of China (NSFC) [61705082, U1701268]
- Natural Science Foundation of Guangdong Province [2017A030313361, 2018030310587]
- Fundamental Research Funds for the Central Universities [21617304]
- Guangdong Province High-Level Talents Introduction Plan [2017GC010420]
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In this study, we presented a high-resolution linear-scanning photoacoustic computed tomography (PACT) system with a focus-tunable fiber-laser ultrasound sensor. By bending the fiber laser into a curvature radius of 25mm, an 85 mu mx150 mu m in-plane resolution and a 300 mu m elevational resolution were achieved. The elevational resolution was similar to 3 times better than the previously reported value. Hair phantoms at multiple depths from 2cm to 6cm were clearly observed by tuning the bending curvature. Additionally, the fiber-laser-based PACT system showed its capability for high-resolution imaging of small animals based on the images of abdominal subcutaneous vasculatures from a rat. With the excitation light delivered by a fiber bundle and the ultrasound detected by a fiber laser, this all-fiber linear-scanning PACT system holds great potential for photoacoustic imaging in preclinical and clinical applications. Published under license by AIP Publishing.
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