Journal
APPLIED ORGANOMETALLIC CHEMISTRY
Volume 34, Issue 8, Pages -Publisher
WILEY
DOI: 10.1002/aoc.5681
Keywords
4H-Pyrimido[2; 1-b]benzothiazoles; fused heterocyclic compounds; nicotine-based ionic liquid; selective synthesis; solvent-free conditions
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Funding
- Research Council of the University of Isfahan
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In this study, an acidic nicotine-based ionic liquid supported on magnetic nanoparticles ([NicTC]HSO4@MNPs) was synthesized and characterized by different techniques. The activity of this catalyst was evaluated in a multi-component reaction of 2-aminobenzothiazole, aldehydes/dialdehydes and beta-ketoesters/1,3-diketones to afford a series of novel mono- and bis-4H-pyrimido[2,1-b]benzothiazole derivatives. In addition, mild reaction conditions, high yields, excellent selectivity as well as easy recovery and reusability of the catalyst, make this method an economic and environmentally-benign process.
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