Journal
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume 104, Issue 10, Pages 4247-4257Publisher
SPRINGER
DOI: 10.1007/s00253-020-10532-z
Keywords
Melanin; Fungi; Extremophile; Astrobiology; Phagocytosis; Antifungal
Categories
Funding
- Professional Staff Congress of the City University of New York [61360-00 49, 61442-00 49]
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Melanins provide fungi protection from environmental stressors, support their ecological roles, and can confer virulence in pathogens. While the function, structure, and synthesis of melanins in fungi are not fully understood, they have been shown to have varied roles. Recent research has revealed a wide range of functions, from radiation resistance to increasing virulence, shedding light on fungal diversity. Understanding fungal melanins can provide useful information, from harnessing the properties of these various melanins to targeting fungal infections. Key Points center dot Melanotic fungi are widespread in nature. center dot Melanin functions to protect fungi in the environment from a range of stresses. center dot Melanin contributes to pathogenesis and drug resistance of pathogenic fungi.
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