Related references
Note: Only part of the references are listed.Resurrection and Reactivation of Acetylcholinesterase and Butyrylcholinesterase
Andrew J. Franjesevic et al.
CHEMISTRY-A EUROPEAN JOURNAL (2019)
Kinetic analysis of oxime-assisted reactivation of human, Guinea pig, and rat acetylcholinesterase inhibited by the organophosphorus pesticide metabolite phorate oxon (PHO)
Robert A. Moyer et al.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY (2018)
Optimization of Cholinesterase-Based Catalytic Bioscavengers Against Organophosphorus Agents
Sofya V. Lushchekina et al.
FRONTIERS IN PHARMACOLOGY (2018)
Evaluating the broad-spectrum efficacy of the acetylcholinesterase oximes reactivators MMB4 DMS, HLo-7 DMS, and 2-PAM Cl against phorate oxon, sarin, and VX in the Hartley guinea pig
Christina M. Wilhelm et al.
NEUROTOXICOLOGY (2018)
Catalytic bioscavengers against organophosphorus agents: mechanistic issues of self-reactivating cholinesterases
Sofya Lushchekina et al.
TOXICOLOGY (2018)
An improved radiosynthesis of O-(2-[18F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: A first-in-class cholinesterase PET tracer
Kiel D. Neumann et al.
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS (2017)
Brief isoflurane administration as a post-exposure treatment for organophosphate poisoning
Jishnu K. S. Krishnan et al.
NEUROTOXICOLOGY (2017)
Acetylcholinesterase measurement in various brain regions and muscles of juvenile, adolescent, and adult rats
Volker Strauss et al.
TOXICOLOGY MECHANISMS AND METHODS (2017)
Acetylcholinesterase measurement in various brain regions and muscles of juvenile, adolescent, and adult rats
Volker Strauss et al.
TOXICOLOGY MECHANISMS AND METHODS (2017)
Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor
Yvonne J. Rosenberg et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2017)
Efforts toward treatments against aging of organophosphorus-inhibited acetylcholinesterase
Qinggeng Zhuang et al.
COUNTERMEASURES AGAINST CHEMICAL THREATS (2016)
Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases
Chih-Kai Chao et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2016)
Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents
C. Linn Cadieux et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
Emergence of catalytic bioscavengers against organophosphorus agents
Patrick Masson et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2016)
A Novel Fluorine-18 β-Fluoroethoxy Organophosphate Positron Emission Tomography Imaging Tracer Targeted to Central Nervous System Acetylcholinesterase
Shelly L. James et al.
ACS CHEMICAL NEUROSCIENCE (2014)
A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides
Christina M. Wilhelm et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
Synthesis and anti-acetylcholinesterase properties of novel β- and γ-substituted alkoxy organophosphonates
S. Kaleem Ahmed et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Centrally acting oximes in reactivation of tabun-phosphoramidated AChE
Zrinka Kovarik et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2013)
Use of functional imaging across clinical phases in CNS drug development
D. Borsook et al.
TRANSLATIONAL PSYCHIATRY (2013)
Refinement of Structural Leads for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases
Zoran Radic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
New Structural Scaffolds for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases
Rakesh K. Sit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach
Franz Worek et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2011)
Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain
Kay Ahn et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
In vivo reactivation by oximes of inhibited blood, brain and peripheral tissue cholinesterase activity following exposure to nerve agents in guinea pigs
Tsung-Ming Shih et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2010)
Treatment with Tertiary Oximes Prevents Seizures and Improves Survival Following Sarin Intoxication
Tsung-Ming Shih et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2010)
The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development
Dean F. Wong et al.
NEUROPSYCHOPHARMACOLOGY (2009)
Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose
Tsung -Ming Shih et al.
TOXICOLOGY MECHANISMS AND METHODS (2009)
Molecular imaging with PET
Simon M. Ametamey et al.
CHEMICAL REVIEWS (2008)
Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS
Sou Okuno et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)
Cholinesterase reactivators: The fate and effects in the organism poisoned with organophosphates/nerve agents
J. Bajgar et al.
CURRENT DRUG METABOLISM (2007)
In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia™) as a potential nerve agent bioscavenger
DM Cerasoli et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2005)
Organic phosphorus compounds - Nerve agents
CL Barthold et al.
CRITICAL CARE CLINICS (2005)
OP or Not OP: The Medical Challenge at the Chemical Terrorism Scene
Amir Krivoy et al.
PREHOSPITAL AND DISASTER MEDICINE (2005)
Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon
I Petrikovics et al.
TOXICOLOGICAL SCIENCES (2004)
Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate
KM George et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Pralidoxime iodide (2-PAM) penetrates across the blood-brain barrier
K Sakurada et al.
NEUROCHEMICAL RESEARCH (2003)
Mechanism of organophosphates (nerve gases and pesticides) and antidotes: Electron transfer and oxidative stress
P Kovacic
CURRENT MEDICINAL CHEMISTRY (2003)
Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates
F Worek et al.
ARCHIVES OF TOXICOLOGY (2002)
A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans
C Timchalk et al.
TOXICOLOGICAL SCIENCES (2002)
Resolving pathways of interaction of covalent inhibitors with the active site of acetylcholinesterases: MALDI-TOF/MS analysis of various nerve agent phosphyl adducts
E Elhanany et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2001)
Share Paper
