Related references
Note: Only part of the references are listed.Sigma-1 receptor protects against ferroptosis in hepatocellular carcinoma cells
Tao Bai et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
Targeting transcription factors in cancer - from undruggable to reality
John H. Bushweller
NATURE REVIEWS CANCER (2019)
Antineoplastic effects of auranofin in human pancreatic adenocarcinoma preclinical models
Mayrim V. Rios Perez et al.
SURGERY OPEN SCIENCE (2019)
Chemotherapy for hepatocellular carcinoma: current status and future perspectives
Masafumi Ikeda et al.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2018)
Beyond malaria: The inhibition of viruses by artemisinin-type compounds
Thomas Efferth
BIOTECHNOLOGY ADVANCES (2018)
Cationic and Neutral N-Heterocyclic Carbene Gold(I) Complexes: Cytotoxicity, NCI-60 Screening, Cellular Uptake, Inhibition of Mammalian Thioredoxin Reductase, and Reactive Oxygen Species Formation
Chen Zhang et al.
CHEMMEDCHEM (2018)
Anticancer metal-N-heterocyclic carbene complexes of gold, platinum and palladium
Taotao Zou et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2018)
New insights in Au-NHCs complexes as anticancer agents
Marina Porchia et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
THE KEAP1-NRF2 SYSTEM: A THIOL-BASED SENSOR-EFFECTOR APPARATUS FOR MAINTAINING REDOX HOMEOSTASIS
Masayuki Yamamoto et al.
PHYSIOLOGICAL REVIEWS (2018)
Pharmacomodulation on Gold-NHC complexes for anticancer applications - is lipophilicity the key point?
Chen Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action
Yin Kwan Wong et al.
MEDICINAL RESEARCH REVIEWS (2017)
From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
Thomas Efferth
SEMINARS IN CANCER BIOLOGY (2017)
Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species
Hui Wang et al.
ONCOTARGET (2017)
Targeting NF-kappa B Signaling by Artesunate Restores Sensitivity of Castrate-Resistant Prostate Cancer Cells to Antiandrogens
Jessica J. Nunes et al.
NEOPLASIA (2017)
Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis
Jong-Lyel Roh et al.
REDOX BIOLOGY (2017)
Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications
Sophie Jurgens et al.
CHIMIA (2017)
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
Xiaofang Sun et al.
HEPATOLOGY (2016)
Mechanism-Guided Design and Synthesis of a Mitochondria-Targeting Artemisinin Analogue with Enhanced Anticancer Activity
Chong-Jing Zhang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Update on metal N-heterocyclic carbene complexes as potential anti-tumor Metallodrugs
Wukun Liu et al.
COORDINATION CHEMISTRY REVIEWS (2016)
Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters
Xupeng Bai et al.
DRUG METABOLISM REVIEWS (2016)
Artemisitene activates the Nrf2-dependent antioxidant response and protects against bleomycin-induced lung injury
Weimin Chen et al.
FASEB JOURNAL (2016)
BRCA1 deficiency increases the sensitivity of ovarian cancer cells to auranofin
Deepu Oommen et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2016)
Targeting antioxidant pathways with ferrocenylated N-heterocyclic carbene supported gold(I) complexes in A549 lung cancer cells
J. F. Arambula et al.
CHEMICAL SCIENCE (2016)
Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells
Genki Tanaka et al.
CANCER MEDICINE (2016)
Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma
Prahlad V. Raninga et al.
REDOX BIOLOGY (2016)
Synthesis, characterization, and antileishmanial activities of gold(I) complexes involving quinoline functionalized N-heterocyclic carbenes
Lucie Paloque et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: A novel synergistic therapeutic approach
Michelle Kiebala et al.
EXPERIMENTAL HEMATOLOGY (2015)
NRF2/KEAP1 and Wnt/-catenin in the multistep process of liver carcinogenesis in humans and rats
Jean-Charles Nault et al.
HEPATOLOGY (2015)
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
Kornelius Schulze et al.
NATURE GENETICS (2015)
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
Edna Ooko et al.
PHYTOMEDICINE (2015)
Auranofin: Repurposing an Old Drug for a Golden New Age
Christine Roder et al.
DRUGS IN R&D (2015)
Gold(I) Biscarbene Complexes Derived from Vascular-Disrupting Combretastatin A-4 Address Different Targets and Show Antimetastatic Potential
Julienne K. Muenzner et al.
CHEMMEDCHEM (2014)
Cytotoxic Gold(I) N-heterocyclic Carbene Complexes with Phosphane Ligands as Potent Enzyme Inhibitors
Riccardo Rubbiani et al.
CHEMMEDCHEM (2014)
Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent
Yves-Paul Vandewynckel et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2014)
Synthesis, structures, and selective toxicity to cancer cells of gold(I) complexes involving N-heterocyclic carbene ligands
Luca Boselli et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Trans-ancestry mutational landscape of hepatocellular carcinoma genomes
Yasushi Totoki et al.
NATURE GENETICS (2014)
NF-κB, an Active Player in Human Cancers
Yifeng Xia et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Toward clinical application of the Keap1-Nrf2 pathway
Takafumi Suzuki et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Yoichiro Mitsuishi et al.
CANCER CELL (2012)
Hypoxia-Inducible Factors in Physiology and Medicine
Gregg L. Semenza
CELL (2012)
Synthesis, Characterization, and in Vitro Studies of Bis[1,3-diethyl-4,5-diarylimidazol-2-ylidene]gold(I/III) Complexes
Wukun Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Comparative in Vitro Evaluation of N-Heterocyclic Carbene Gold(I) Complexes of the Benzimidazolylidene Type
Riccardo Rubbiani et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity
Aya Nakaya et al.
LEUKEMIA RESEARCH (2011)
Inflammation meets cancer, with NF-κB as the matchmaker
Yinon Ben-Neriah et al.
NATURE IMMUNOLOGY (2011)
Dihydroartemisinin inactivates NF-κB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo
Shuang-Jia Wang et al.
CANCER LETTERS (2010)
Artemisinins: their growing importance in medicine
Sanjeev Krishna et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1α activation in C6 glioma cells
Xiao-Jia Huang et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2007)
Hypoxia in cancer: significance and impact on clinical outcome
Peter Vaupel et al.
CANCER AND METASTASIS REVIEWS (2007)
Dihydroartemisinin inhibits angiogenesis induced by multiple myeloma RPMI8226 cells under hypoxic conditions via downregulation of vascular endothelial growth factor expression and suppression of vascular endothelial growth factor secretion
Xiu-Hua Wu et al.
ANTI-CANCER DRUGS (2006)
Targeting multidrug resistance in cancer
G Szakács et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Clonogenic assay of cells in vitro
Nicolaas A. P. Franken et al.
NATURE PROTOCOLS (2006)
β2-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein
CH Wu et al.
ONCOGENE (2001)
Multidrug resistance in haematological malignancies
P Sonneveld
JOURNAL OF INTERNAL MEDICINE (2000)