4.4 Review

Evaluation of seminal Oxidation-Reduction potential in male infertility

Journal

ANDROLOGIA
Volume 53, Issue 2, Pages -

Publisher

WILEY
DOI: 10.1111/and.13610

Keywords

male infertility; oxidation-reduction potential; oxidative stress

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ORP as a new oxidative stress marker plays an important role in evaluating semen quality and male fertility status, but further research is needed to establish its use in assisted reproductive techniques practice.
The role of oxidative stress in male infertility has been broadly recognised, and the search for a new marker to determine the redox environment in semen has gained considerable interest. Oxidation-reduction potential (ORP) or redox potential, is a measure of the electron transfer from antioxidants to oxidants and provides information on the redox balance. In this review, the benefits of ORP as a new oxidative stress marker, the protocol for its evaluation and the importance of its measurement in the context of male infertility are discussed. In association with the standard semen analysis, seminal ORP has been analysed to evaluate semen quality and male fertility status. However, further studies are required to establish its use in assisted reproductive techniques (ART) practice.

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