Journal
ANALYTICAL CHEMISTRY
Volume 92, Issue 9, Pages 6251-6256Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.0c00814
Keywords
-
Categories
Ask authors/readers for more resources
An easy-to-implement strategy of differential flow modulation for comprehensive two-dimensional gas chromatography was innovated. With this approach, an independent auxiliary pneumatic control device for flow modulation was not a prerequisite. The strategy involved splitting the carrier gas stream into two separate streams before reaching the inlet embodiment. One stream was employed as a mobile phase for chromatographic separation. The other stream, for flow modulation, was routed to one of the ports of a three-way solenoid valve. The modulation stream flowed onward to a fluidic path and a T-junction that joined the primary and secondary dimension columns. With this arrangement and depending on the configuration of the three-port valve, the analytical platform can be operated in three different modes: bypass stop-flow, vent stop-flow, and quasi-stop flow. Quasi-stop-flow mode was demonstrated to have a significantly better chromatographic performance, as demonstrated in various types of real-life petroleum samples such as gasoline and light cycle oil. In the light cycle oil sample, a respectable separation between compound classes was achieved with peak width at half height of 34 ms or less for alkanes on a second dimension with polyethylene glycol stationary phase. Excellent repeatability was shown with normal alkanes standards of nC(8)-nC(25). Relative standard deviations for retention times are almost zero in D-1, less than 0.2% in D-2, and less than 3.5% for peak areas (n = 9).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available