4.6 Article

COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine

Journal

AMERICAN JOURNAL OF TRANSPLANTATION
Volume 20, Issue 7, Pages 1902-1906

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1111/ajt.15935

Keywords

clinical research; practice; immunosuppressant - fusion proteins and monoclonal antibodies; infection and infectious agents - viral; infectious disease; kidney transplantation; nephrology

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Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, transplant clinicians should be readily informed about new cases of COVID-19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome.

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