Journal
AIDS
Volume 34, Issue 8, Pages 1107-1116Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/QAD.0000000000002518
Keywords
acquired immunodeficiency syndrome; HIV infection; HIV organ policy equity act; kidney transplantation; liver transplantation; organ donors and donation; organ transplantation
Categories
Funding
- NIAID NIH HHS [T32 AI095207] Funding Source: Medline
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With current antiretroviral therapy, the lifespan of newly diagnosed persons with HIV (PWH) approaches that of uninfected persons. However, metabolic abnormalities related to both the disease and the virus itself, along with comorbidities of aging, have resulted in end-organ disease and organ failure as a major cause of morbidity and mortality. Solid organ transplantation is a life-saving therapy for PWH who have organ failure, and the approval of the HIV Organ Policy Equity Act has opened and expanded opportunities for PWH to donate and receive organs. The current environment of organ transplantation for PWH will be reviewed and future directions of research and treatment will be discussed.
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