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RSC ADVANCES (2016)
A collagen-binding EGFR antibody fragment targeting tumors with a collagen-rich extracellular matrix
Hui Liang et al.
SCIENTIFIC REPORTS (2016)
Multiple Administrations of Viral Nanoparticles Alter in Vivo Behavior-Insights from Intravital Microscopy
Sourabh Shukla et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)
Longitudinal Intravital Imaging of the Retina Reveals Long-term Dynamics of Immune Infiltration and Its Effects on the Glial Network in Experimental Autoimmune Uveoretinitis, without Evident Signs of Neuronal Dysfunction in the Ganglion Cell Layer
Daniel Bremer et al.
FRONTIERS IN IMMUNOLOGY (2016)
Multiple Administrations of Viral Nanoparticles Alter in Vivo Behavior-Insights from Intravital Microscopy
Sourabh Shukla et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)
A soft, transparent, freely accessible cranial window for chronic imaging and electrophysiology
Chaejeong Heo et al.
SCIENTIFIC REPORTS (2016)
Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies
Capucine L. Grandjean et al.
SCIENTIFIC REPORTS (2016)
Radioactive Nanomaterials for Multimodality Imaging
Daiqin Chen et al.
TOMOGRAPHY (2016)
Alk5 inhibition increases delivery of macromolecular and protein-bound contrast agents to tumors
Heike E. Daldrup-Link et al.
JCI INSIGHT (2016)
Positron Emission Tomography Imaging Using Radio labeled Inorganic Nanomaterials
Xiaolian Sun et al.
ACCOUNTS OF CHEMICAL RESEARCH (2015)
Antigen-Loaded Upconversion Nanoparticles for Dendritic Cell Stimulation, Tracking, and Vaccination in Dendritic Cell-Based Immunotherapy
Jian Xiang et al.
ACS NANO (2015)
Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection
Dafeng Chu et al.
ACS NANO (2015)
Remodeling Tumor Vasculature to Enhance Delivery of Intermediate-Sized Nanoparticles
Wen Jiang et al.
ACS NANO (2015)
Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity
Hiroshi Maeda
ADVANCED DRUG DELIVERY REVIEWS (2015)
Fluorescent pH Sensors for Broad-Range pH Measurement Based on a Single Fluorophore
Jing Qi et al.
ANALYTICAL CHEMISTRY (2015)
Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression
Eunha Kim et al.
BIOCONJUGATE CHEMISTRY (2015)
Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling
Eishu Hirata et al.
CANCER CELL (2015)
Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
Alexander F. Bagley et al.
CANCER RESEARCH (2015)
Clarifying Tissue Clearing
Douglas S. Richardson et al.
CELL (2015)
Recent developments in multiplexing techniques for immunohistochemistry
Angela R. Dixon et al.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2015)
Ultrasound in Radiology From Anatomic, Functional, Molecular Imaging to Drug Delivery and Image-Guided Therapy
Alexander L. Klibanov et al.
INVESTIGATIVE RADIOLOGY (2015)
Long-Term Survival Advantage and Prognostic Factors Associated With Intraperitoneal Chemotherapy Treatment in Advanced Ovarian Cancer: A Gynecologic Oncology Group Study
Devansu Tewari et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Polymeric micelles and nanoemulsions as tumor-targeted drug carriers: Insight through intravital imaging
Natalya Rapoport et al.
JOURNAL OF CONTROLLED RELEASE (2015)
SOD1 nanozyme salvages ischemic brain by locally protecting cerebral vasculature
Yuhang Jiang et al.
JOURNAL OF CONTROLLED RELEASE (2015)
MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice
Michaela Aichler et al.
LABORATORY INVESTIGATION (2015)
Extracellular rigidity sensing by talin isoform-specific mechanical linkages
Katharina Austen et al.
NATURE CELL BIOLOGY (2015)
Continuous volumetric imaging via an optical phase-locked ultrasound lens
Lingjie Kong et al.
NATURE METHODS (2015)
High-resolution whole-brain staining for electron microscopic circuit reconstruction
Shawn Mikula et al.
NATURE METHODS (2015)
In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy
Deepak R. Chittajallu et al.
NATURE METHODS (2015)
High-speed label-free functional photoacoustic microscopy of mouse brain in action
Junjie Yao et al.
NATURE METHODS (2015)
Advances in real-time multispectral optoacoustic imaging and its applications
Adrian Taruttis et al.
NATURE PHOTONICS (2015)
Imaging the beating heart in the mouse using intravital microscopy techniques
Claudio Vinegoni et al.
NATURE PROTOCOLS (2015)
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
Jennifer B. Treweek et al.
NATURE PROTOCOLS (2015)
In Vivo Fluorescence Microscopy: Lessons From Observing Cell Behavior in Their Native Environment
Myunghwan Choi et al.
PHYSIOLOGY (2015)
Using bimodal MRI/fluorescence imaging to identify host angiogenic response to implants
Alexandra Berdichevski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Regulation of dendrimer/dextran material performance by altered tissue microenvironment in inflammation and neoplasia
Nuria Oliva et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle
Miles A. Miller et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Self-assembled hydrogels utilizing polymer-nanoparticle interactions
Eric A. Appel et al.
NATURE COMMUNICATIONS (2015)
Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes
Henry R. Hampton et al.
NATURE COMMUNICATIONS (2015)
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug
Miles A. Miller et al.
NATURE COMMUNICATIONS (2015)
Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA
Allison S. Harney et al.
CANCER DISCOVERY (2015)
Single cell resolution in vivo imaging of DNA damage following PARP inhibition
Katherine S. Yang et al.
SCIENTIFIC REPORTS (2015)
Fully automatic and robust 3D registration of serial-section microscopic images
Ching-Wei Wang et al.
SCIENTIFIC REPORTS (2015)
Effect of Shape, Size, and Aspect Ratio on Nanoparticle Penetration and Distribution inside Solid Tissues Using 3D Spheroid Models
Rachit Agarwal et al.
ADVANCED HEALTHCARE MATERIALS (2015)
Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment
Nuria Oliva et al.
ADVANCED HEALTHCARE MATERIALS (2015)
Application of functional quantum dot nanoparticles as fluorescence probes in cell labeling and tumor diagnostic imaging
Mei-Xia Zhao et al.
NANOSCALE RESEARCH LETTERS (2015)
Real-Time Intravital Imaging Establishes Tumor-Associated Macrophages as the Extraskeletal Target of Bisphosphonate Action in Cancer
Simon Junankar et al.
CANCER DISCOVERY (2015)
A Robust Approach to Enhance Tumor-selective Accumulation of Nanoparticles
Yuan Qiao et al.
Oncotarget (2015)
Development of subcutaneous sustained release nanoparticles encapsulating low molecular weight heparin
Satheesh Jogala et al.
JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH (2015)
In Vivo Nanoparticle Assessment of Pathological Endothelium Predicts the Development of Inflow Stenosis in Murine Arteriovenous Fistula
Jie Cui et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)
iDISCO: A Simple, RapidMethod to Immunolabel Large Tissue Samples for Volume Imaging
Nicolas Renier et al.
CELL (2014)
Platinum Compounds for High-Resolution In Vivo Cancer Imaging
Miles A. Miller et al.
CHEMMEDCHEM (2014)
In vivo endomicroscopy improves detection of Barrett's esophagus-related neoplasia: a multicenter international randomized controlled trial (with video)
Marcia Irene Canto et al.
GASTROINTESTINAL ENDOSCOPY (2014)
Multimodality PET/MRI agents targeted to activated macrophages
Chuqiao Tu et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2014)
Strategies to overcome photobleaching in algorithm-based adaptive optics for nonlinear in-vivo imaging
M. Caroline Muellenbroich et al.
JOURNAL OF BIOMEDICAL OPTICS (2014)
Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan
Aditya G. Kohli et al.
JOURNAL OF CONTROLLED RELEASE (2014)
Controlled release for local delivery of drugs: barriers and models
Jennifer R. Weiser et al.
JOURNAL OF CONTROLLED RELEASE (2014)
Ultrashort Echo Time (UTE) Imaging of Receptor Targeted Magnetic Iron Oxide Nanoparticles in Mouse Tumor Models
Liya Wang et al.
JOURNAL OF MAGNETIC RESONANCE IMAGING (2014)
Ado-trastuzumab Emtansine (T-DM1): An Antibody-Drug Conjugate (ADC) for HER2-Positive Breast Cancer
John M. Lambert et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Sustained Delivery of VEGF Maintains Innervation and Promotes Reperfusion in Ischemic Skeletal Muscles Via NGF/GDNF Signaling
Dmitry Shvartsman et al.
MOLECULAR THERAPY (2014)
Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging
Laila Ritsma et al.
NATURE (2014)
Imaging macrophages with nanoparticles
Ralph Weissleder et al.
NATURE MATERIALS (2014)
Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery
Bryan Ronain Smith et al.
NATURE NANOTECHNOLOGY (2014)
Prevention of vascular inflammation by nanoparticle targeting of adherent neutrophils
Zhenjia Wang et al.
NATURE NANOTECHNOLOGY (2014)
Removable cranial windows for long-term imaging in awake mice
Glenn J. Goldey et al.
NATURE PROTOCOLS (2014)
Multiplexed immunohistochemistry, imaging, and quantitation: A review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysis
Edward C. Stack et al.
METHODS (2014)
Intravital imaging of cardiac function at the single-cell level
Aaron D. Aguirre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations
Marja Lohela et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution
Bi-Chang Chen et al.
SCIENCE (2014)
Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin
Ashley M. Laughney et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
In vivo imaging of specific drug-target binding at subcellular resolution
J. M. Dubach et al.
NATURE COMMUNICATIONS (2014)
Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach
Jason T. Weiss et al.
NATURE COMMUNICATIONS (2014)
Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles
Adrian T. Press et al.
NATURE COMMUNICATIONS (2014)
Single cell imaging of Bruton's Tyrosine Kinase using an irreversible inhibitor
Anna Turetsky et al.
SCIENTIFIC REPORTS (2014)
Real- Time Noninvasive Monitoring of In Vivo Infl ammatory Responses using a pH Ratiometric Fluorescence Imaging Probe
Yi-Ting Tsai et al.
ADVANCED HEALTHCARE MATERIALS (2014)
Cytotoxic T Lymphocyte Antigen-4 Blockade Enhances Antitumor Immunity by Stimulating Melanoma-Specific T-cell Motility
Tsvetelina Pentcheva-Hoang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
In Vivo Imaging of Microglia Turnover in the Mouse Retina After Ionizing Radiation and Dexamethasone Treatment
Clemens Alt et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)
Limitations of the dorsal skinfold window chamber model in evaluating anti-angiogenic therapy during early phase of angiogenesis
Nikolett M. Biel et al.
VASCULAR CELL (2014)
Near-Infrared Fluorescence Energy Transfer Imaging of Nanoparticle Accumulation and Dissociation Kinetics in Tumor-Bearing Mice
Yiming Zhao et al.
ACS NANO (2013)
The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo
Hiroshi Maeda et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
Superior Penetration and Retention Behavior of 50 nm Gold Nanoparticles in Tumors
Shuaidong Huo et al.
CANCER RESEARCH (2013)
Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer
Max Nobis et al.
CANCER RESEARCH (2013)
Benefits of Vascular Normalization Are Dose and Time Dependent-Letter
Yuhui Huang et al.
CANCER RESEARCH (2013)
Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter
Takaya Abe et al.
DEVELOPMENT (2013)
Image-guided drug delivery to the brain using nanotechnology
Hong Ding et al.
DRUG DISCOVERY TODAY (2013)
The Transcription Factor NFAT Exhibits Signal Memory during Serial T Cell Interactions with Antigen-Presenting Cells
Francesco Marangoni et al.
IMMUNITY (2013)
Nanoparticle clearance is governed by Th1/Th2 immunity and strain background
Stephen W. Jones et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy
Li Li et al.
JOURNAL OF CONTROLLED RELEASE (2013)
Therapeutic Targeting of the Axonal and Microvascular Change Associated with Repetitive Mild Traumatic Brain Injury
Takashi Miyauchi et al.
JOURNAL OF NEUROTRAUMA (2013)
Fluorescent labeling of chitosan for use in non-invasive monitoring of degradation in tissue engineering
Cassilda Cunha-Reis et al.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2013)
High-Resolution Optical Mapping of Inflammatory Macrophages Following Endovascular Arterial Injury
Amit Saxena et al.
MOLECULAR IMAGING AND BIOLOGY (2013)
High-resolution, serial intravital microscopic imaging of nanoparticle delivery and targeting in a small animal tumor model
Bryan Ronain Smith et al.
NANO TODAY (2013)
Spatial organization within a niche as a determinant of stem-cell fate
Panteleimon Rompolas et al.
NATURE (2013)
Advances in multiphoton microscopy technology
Erich E. Hoover et al.
NATURE PHOTONICS (2013)
Surgical implantation of an abdominal imaging window for intravital microscopy
Laila Ritsma et al.
NATURE PROTOCOLS (2013)
Improved preparation of acellular nerve scaffold and application of PKH26 fluorescent labeling combined with in vivo fluorescent imaging system in nerve tissue engineering
Zhao Bin et al.
NEUROSCIENCE LETTERS (2013)
Intravital Immunofluorescence for Visualizing the Microcirculatory and Immune Microenvironments in the Mouse Ear Dermis
Witold W. Kilarski et al.
PLOS ONE (2013)
Intravital FRET Imaging of Tumor Cell Viability and Mitosis during Chemotherapy
Aniek Janssen et al.
PLOS ONE (2013)
Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier
Daren Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Particle shape enhances specificity of antibody-displaying nanoparticles
Sutapa Barua et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Brief Report: Intravital Imaging of Cancer Stem Cell Plasticity in Mammary Tumors
Anoek Zomer et al.
STEM CELLS (2013)
Electrochemical Failure of the Brain Cortex Is More Deleterious When it Is Accompanied by Low Perfusion
Jens P. Dreier et al.
STROKE (2013)
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
Vikash P. Chauhan et al.
NATURE COMMUNICATIONS (2013)
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo
Greg M. Thurber et al.
NATURE COMMUNICATIONS (2013)
Intravital Microscopic Research of Microembolization with Degradable Starch Microspheres
Micaela Ebert et al.
JOURNAL OF DRUG DELIVERY (2013)
Peptide Imaging with Somatostatin Analogues: More than Cancer Probes
Giuseppe Lucio Cascini et al.
CURRENT RADIOPHARMACEUTICALS (2013)
Visualizing Dynamics of Sub-Hepatic Distribution of Nanoparticles Using Intravital Multiphoton Fluorescence Microscopy
Shih-Hsun Cheng et al.
ACS NANO (2012)
(α-NaYbF4:Tm3+)/CaF2 Core/Shell Nanoparticles with Efficient Near-Infrared to Near-Infrared Upconversion for High-Contrast Deep Tissue Bioimaging
Guanying Chen et al.
ACS NANO (2012)
The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems
Alexandre Albanese et al.
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 14 (2012)
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
Paolo P. Provenzano et al.
CANCER CELL (2012)
Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging
Tengfei Li et al.
FASEB JOURNAL (2012)
Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics
Anh H. Pham et al.
GENESIS (2012)
Histo-Cytometry: A Method for Highly Multiplex Quantitative Tissue Imaging Analysis Applied to Dendritic Cell Subset Microanatomy in Lymph Nodes
Michael Y. Gerner et al.
IMMUNITY (2012)
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
Eleonore Froehlich
INTERNATIONAL JOURNAL OF NANOMEDICINE (2012)
Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain
Andy Y. Shih et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects
Maria Grazia Ruocco et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Doxil® - The first FDA-approved nano-drug: Lessons learned
Yechezkel (Chezy) Barenholz
JOURNAL OF CONTROLLED RELEASE (2012)
Polymeric nanoparticles as OCT contrast agents
Wa'el Al Rawashdeh et al.
JOURNAL OF NANOPARTICLE RESEARCH (2012)
Quantitative, Simultaneous PET/MRI for Intratumoral Imaging with an MRI-Compatible PET Scanner
Thomas S. C. Ng et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Ultrasound Microbubbles for Molecular Diagnosis, Therapy, and Theranostics
Fabian Kiessling et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
The peritoneal tumour microenvironment of high-grade serous ovarian cancer
D. Andrew Leinster et al.
JOURNAL OF PATHOLOGY (2012)
Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake
Carl D. Walkey et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Metabolic Imaging Using Two-Photon Excited NADH Intensity and Fluorescence Lifetime Imaging
Jorge Vergen et al.
MICROSCOPY AND MICROANALYSIS (2012)
Shape Matters: Intravital Microscopy Reveals Surprising Geometrical Dependence for Nanoparticles in Tumor Models of Extravasation
Bryan Ronain Smith et al.
NANO LETTERS (2012)
HIV-infected T cells are migratory vehicles for viral dissemination
Thomas T. Murooka et al.
NATURE (2012)
FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed tomography
Angelique Ale et al.
NATURE METHODS (2012)
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
Vikash P. Chauhan et al.
NATURE NANOTECHNOLOGY (2012)
Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure
Xiyi Chen et al.
NATURE PROTOCOLS (2012)
In vivo real-time imaging of chemotherapy response on the liver metastatic tumor microenvironment using multiphoton microscopy
Koji Tanaka et al.
ONCOLOGY REPORTS (2012)
High Resolution Intravital Imaging of Subcellular Structures of Mouse Abdominal Organs Using a Microstage Device
Liqin Cao et al.
PLOS ONE (2012)
Characterization and adaptive optical correction of aberrations during in vivo imaging in the mouse cortex
Na Jia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases
David P. Kodack et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Aberration-free three-dimensional multiphoton imaging of neuronal activity at kHz rates
Edward J. Botcherby et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma
Jieqiong Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Intravital Microscopy Through an Abdominal Imaging Window Reveals a Pre-Micrometastasis Stage During Liver Metastasis
Laila Ritsma et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Preparation of Quantum Dot/Drug Nanoparticle Formulations for Traceable Targeted Delivery and Therapy
Ken-Tye Yong et al.
THERANOSTICS (2012)
Fluorescence-Tagged Gold Nanoparticles for Rapidly Characterizing the Size-Dependent Biodistribution in Tumor Models
Leo Y. T. Chou et al.
ADVANCED HEALTHCARE MATERIALS (2012)
Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy
Carlos Tassa et al.
ACCOUNTS OF CHEMICAL RESEARCH (2011)
Tumor delivery of macromolecular drugs based on the EPR effect
Vladimir Torchilin
ADVANCED DRUG DELIVERY REVIEWS (2011)
Intravital microscopy as a tool to study drug delivery in preclinical studies
Panomwat Amornphimoltham et al.
ADVANCED DRUG DELIVERY REVIEWS (2011)
Assembly and Targeting of Liposomal Nanoparticles Encapsulating Quantum Dots
Rajesh Mukthavaram et al.
BIOCONJUGATE CHEMISTRY (2011)
Fluorescence Labeling of Carbon Nanotubes and Visualization of a Nanotube-Protein Hybrid under Fluorescence Microscope
Shige H. Yoshimura et al.
BIOMACROMOLECULES (2011)
Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics
James D. Orth et al.
CANCER RESEARCH (2011)
Establishment of Conditional Reporter Mouse Lines at ROSA26 Locus For Live Cell Imaging
Takaya Abe et al.
GENESIS (2011)
Intravital microscopy: new insights into metastasis of tumors
Evelyne Beerling et al.
JOURNAL OF CELL SCIENCE (2011)
Temporal changes in microvessel leakiness during wound healing discriminated by in vivo fluorescence recovery after photobleaching
Maria J. C. Machado et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Targeted Delivery of Nanoparticles to Ischemic Muscle for Imaging and Therapeutic Angiogenesis
Jaeyun Kim et al.
NANO LETTERS (2011)
Nanoparticles Targeting the Infarcted Heart
Tal Dvir et al.
NANO LETTERS (2011)
How to detect a dwarf: in vivo imaging of nanoparticles in the lung
Jonas Roller et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2011)
Magnetic nanoparticle biodistribution following intratumoral administration
A. J. Giustini et al.
NANOTECHNOLOGY (2011)
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
H. Cabral et al.
NATURE NANOTECHNOLOGY (2011)
NORMALIZATION OF THE VASCULATURE FOR TREATMENT OF CANCER AND OTHER DISEASES
Shom Goel et al.
PHYSIOLOGICAL REVIEWS (2011)
In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles
Christopher M. Jewell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging
Robert M. Koffie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
Benjamin Diop-Frimpong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Engineered cartilage using primary chondrocytes cultured in a porous cartilage-derived matrix
Nai-Chen Cheng et al.
REGENERATIVE MEDICINE (2011)
Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies
Vikash P. Chauhan et al.
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 2 (2011)
Intravital microscopy imaging of macrophage localization to immunogenic particles and co-localized tissue oxygen saturation
Se-woon Choe et al.
ACTA BIOMATERIALIA (2010)
Fluorescent-labeled antibodies: Balancing functionality and degree of labeling
Shaleen Vira et al.
ANALYTICAL BIOCHEMISTRY (2010)
Quantitative In vivo Imaging of the Effects of Inhibiting Integrin Signaling via Src and FAK on Cancer Cell Movement: Effects on E-cadherin Dynamics
Marta Canel et al.
CANCER RESEARCH (2010)
Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
Hugo J. Snippert et al.
CELL (2010)
Imaging with Raman Spectroscopy
Yin Zhang et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2010)
In Vivo Nano-imaging of Membrane Dynamics in Metastatic Tumor Cells Using Quantum Dots
Kohsuke Gonda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Photoacoustic imaging and characterization of the microvasculature
Song Hu et al.
JOURNAL OF BIOMEDICAL OPTICS (2010)
Fluorescently Labeled Gold Nanoparticles with Minimal Fluorescence Quenching
Yin Lu et al.
JOURNAL OF PHYSICAL CHEMISTRY C (2010)
Radiolabeled Small Molecule Protein Kinase Inhibitors for Imaging with PET or SPECT
Justin W. Hicks et al.
MOLECULES (2010)
Quantum Dot and Cy5.5 Labeled Nanoparticles to Investigate Lipoprotein Biointeractions via Forster Resonance Energy Transfer
Torjus Skajaa et al.
NANO LETTERS (2010)
Thinned-skull cranial window technique for long-term imaging of the cortex in live mice
Guang Yang et al.
NATURE PROTOCOLS (2010)
Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo
Samantha A. Morris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Exercise-induced VEGF transcriptional activation in brain, lung and skeletal muscle
Kechun Tang et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2010)
Quantum Dots and Their Multimodal Applications: A Review
Debasis Bera et al.
MATERIALS (2010)
Time-dependent degradation of titanium osteoconductivity: An implication of biological aging of implant materials
Wael Atta et al.
BIOMATERIALS (2009)
Positron Emission Tomography (PET) Imaging with [11C]-Labeled Erlotinib: A Micro-PET Study on Mice with Lung Tumor Xenografts
Ashfaque A. Memon et al.
CANCER RESEARCH (2009)
Intravital imaging of CD8+ T cell function in cancer
Thorsten R. Mempel et al.
CLINICAL & EXPERIMENTAL METASTASIS (2009)
A novel strategy for surface modification of superparamagnetic iron oxide nanoparticles for lung cancer imaging
Gang Huang et al.
JOURNAL OF MATERIALS CHEMISTRY (2009)
In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of 86Y- and 111In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor-Bearing Nude Mice
Douglas W. Schneider et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Flexible Filaments for in Vivo Imaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage
David A. Christian et al.
MOLECULAR PHARMACEUTICS (2009)
Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window
Anthony Holtmaat et al.
NATURE PROTOCOLS (2009)
MAGNETIC RESONANCE IMAGING AND MICRO-COMPUTED TOMOGRAPHY COMBINED ATLAS OF DEVELOPING AND ADULT MOUSE BRAINS FOR STEREOTAXIC SURGERY
M. Aggarwal et al.
NEUROSCIENCE (2009)
Nanoparticle-enabled terahertz imaging for cancer diagnosis
Seung Jae Oh et al.
OPTICS EXPRESS (2009)
Intravascular Delivery of Particulate Systems: Does Geometry Really Matter?
Paolo Decuzzi et al.
PHARMACEUTICAL RESEARCH (2009)
Systematic Surface Engineering of Magnetic Nanoworms for in vivo Tumor Targeting
Ji-Ho Park et al.
SMALL (2009)
Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance
Greg M. Thurber et al.
ADVANCED DRUG DELIVERY REVIEWS (2008)
The receptor-mediated endocytosis of nonspherical particles
P. Decuzzi et al.
BIOPHYSICAL JOURNAL (2008)
Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies
Steven H. Lin et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2008)
Delivery of serotonin to the brain by monocytes following phagocytosis of liposomes
Eyal Afergan et al.
JOURNAL OF CONTROLLED RELEASE (2008)
High-intensity focused ultrasound therapy: An overview for radiologists
Young-Sun Kim et al.
KOREAN JOURNAL OF RADIOLOGY (2008)
Targeted Gold Nanoparticles Enable Molecular CT Imaging of Cancer
Rachela Popovtzer et al.
NANO LETTERS (2008)
Intravital imaging of metastatic behavior through a mammary imaging window
Dmitriy Kedrin et al.
NATURE METHODS (2008)
A practical guide to single-molecule FRET
Rahul Roy et al.
NATURE METHODS (2008)
Nanoparticle-mediated cellular response is size-dependent
Wen Jiang et al.
NATURE NANOTECHNOLOGY (2008)
Molecular imaging in drug development
Juergen K. Willmann et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Improving signal levels in intravital multiphoton microscopy using an objective correction collar
Pamela A. Muriello et al.
OPTICS COMMUNICATIONS (2008)
Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction
Timothy R. Nurkiewicz et al.
PARTICLE AND FIBRE TOXICOLOGY (2008)
Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane
Martin Offterdinger et al.
TRAFFIC (2008)
In vivo imaging of Cu-64-labeled polymer nanoparticles targeted to the lung endothelium
Raffaella Rossin et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy
Kazuhiko Kurozumi et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
A cellular Trojan horse for delivery of therapeutic nanoparticles into tumors
Mi-Ran Choi et al.
NANO LETTERS (2007)
Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system
Jean Livet et al.
NATURE (2007)
Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex
Hua-Tai Xu et al.
NATURE NEUROSCIENCE (2007)
Shape effects of filaments versus spherical particles in flow and drug delivery
Yan Geng et al.
NATURE NANOTECHNOLOGY (2007)
Collagen reorganization at the tumor-stromal interface facilitates local invasion
Paolo P. Provenzano et al.
BMC MEDICINE (2006)
The tyrosine kinase inhibitor PD153035:: implication of labeling position on radiometabolites formed in vitro
Erik Samen et al.
NUCLEAR MEDICINE AND BIOLOGY (2006)
Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems
Twan Lammers et al.
NEOPLASIA (2006)
Synthesis of [11C]Iressa as a new potential PET cancer imaging agent for epidermal growth factor receptor tyrosine kinase
Ji-Quan Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Visualization of IL-12/23p40 in vivo reveals immunostimulatory dendritic cell migrants that promote Th1 differentiation
R. Lee Reinhardt et al.
JOURNAL OF IMMUNOLOGY (2006)
Duration and intensity of NF-κB activity determine the severity of endotoxin-induced acute lung injury
M. Brett Everhart et al.
JOURNAL OF IMMUNOLOGY (2006)
In vivo Imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice
Jerry M. Rhee et al.
GENESIS (2006)
Effect of inhibition of vascular endothelial growth factor signaling on distribution of extravasated antibodies in tumors
T Nakahara et al.
CANCER RESEARCH (2006)
Developmental regulation of Foxp3 expression during ontogeny
JD Fontenot et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Innovation - Reporter mice and drug discovery and development
A Maggi et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Strategy of utilizing in vitro and in vivo ADME tools for lead optimization and drug candidate selection
SK Balani et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)
Site-specific labeling of the ribosome for single-molecule spectroscopy
M Dorywalska et al.
NUCLEIC ACIDS RESEARCH (2005)
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
CG Willett et al.
NATURE MEDICINE (2004)
High interstitial fluid pressure -: An obstacle in cancer therapy
CH Heldin et al.
NATURE REVIEWS CANCER (2004)
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
RT Tong et al.
CANCER RESEARCH (2004)
Visualization of leukocyte transendothelial and interstitial migration using reflected light oblique transillumination in intravital video microscopy
TR Mempel et al.
JOURNAL OF VASCULAR RESEARCH (2003)
Dissecting tumour pathophysiology using intravital microscopy
RK Jain et al.
NATURE REVIEWS CANCER (2002)
Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage
I Kalajzic et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2002)
Non-invasive visualization of sperm mitochondria behavior in transgenic mice with introduced green fluorescent protein (GFP)
H Shitara et al.
FEBS LETTERS (2001)
Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein
T Pratt et al.
DEVELOPMENTAL BIOLOGY (2000)
Analysis of fractalkine receptor CX3CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
S Jung et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
H Maeda et al.
JOURNAL OF CONTROLLED RELEASE (2000)