4.7 Article

Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization

Related references

Note: Only part of the references are listed.
Article Cell & Tissue Engineering

Enhanced tenogenic differentiation and tendon-like tissue formation by tenomodulin overexpression in murine mesenchymal stem cells

Yongkang Jiang et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2017)

Article Biotechnology & Applied Microbiology

A comprehensive map of molecular drug targets

Rita Santos et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Review Pharmacology & Pharmacy

Fibroblast growth factors (FGFs) in cancer: FGF traps as a new therapeutic approach

Marco Presta et al.

PHARMACOLOGY & THERAPEUTICS (2017)

Article Biochemistry & Molecular Biology

Novel Mechanisms for the Antifibrotic Action of Nintedanib

Sunad Rangarajan et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2016)

Article Genetics & Heredity

Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways

Wenbo Wang et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2016)

Review Biochemistry & Molecular Biology

Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment

Jonathan P. Andrews et al.

MATRIX BIOLOGY (2016)

Article Critical Care Medicine

FK506-Binding Protein 10, a Potential Novel Drug Target for Idiopathic Pulmonary Fibrosis

Claudia A. Staab-Weijnitz et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)

Review Respiratory System

Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

Lutz Wollin et al.

EUROPEAN RESPIRATORY JOURNAL (2015)

Article Chemistry, Medicinal

Nintedanib: From Discovery to the Clinic

Gerald J. Roth et al.

JOURNAL OF MEDICINAL CHEMISTRY (2015)

Review Biotechnology & Applied Microbiology

Profile of nintedanib in the treatment of solid tumors: the evidence to date

Niranjan Awasthi et al.

ONCOTARGETS AND THERAPY (2015)

Review Dermatology

Critical Role of Transforming Growth Factor Beta in Different Phases of Wound Healing

Mohammadreza Pakyari et al.

ADVANCES IN WOUND CARE (2013)

Article Engineering, Biomedical

In vivo tendon engineering with skeletal muscle derived cells in a mouse model

Bo Chen et al.

BIOMATERIALS (2012)

Review Cell Biology

PAI-1 in tissue fibrosis

Asish K. Ghosh et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2012)

Article Medical Laboratory Technology

Altered angiogenic balance in keloids: a key to therapeutic intervention

Nirupa Shyam Mogili et al.

TRANSLATIONAL RESEARCH (2012)

Article Dermatology

Human skin keloid fibroblasts display bioenergetics of cancer cells

Annette S. Vincent et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)

Article Dermatology

Effect of heat shock protein 47 on collagen accumulation in keloid fibroblast cells

J.-J. Chen et al.

BRITISH JOURNAL OF DERMATOLOGY (2007)

Article Respiratory System

Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis

N. I. Chaudhary et al.

EUROPEAN RESPIRATORY JOURNAL (2007)

Article Surgery

Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts

Zimin Wang et al.

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY (2007)

Article Surgery

Modulation of collagen synthesis in keloid fibroblasts by silencing Smad2 with siRNA

Zhongyu Gao et al.

PLASTIC AND RECONSTRUCTIVE SURGERY (2006)

Review Pediatrics

Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and management

Alison E. Slemp et al.

CURRENT OPINION IN PEDIATRICS (2006)

Article Physiology

P38 MAP kinase mediates transforming growth factor-β2 transcription in human keloid fibroblasts

W Xia et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)

Review Biochemistry & Molecular Biology

Growth factor receptors, lipid rafts and caveolae: An evolving story

LJ Pike

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)

Review Rheumatology

Pathogenesis of fibrosis:: role of TGF-β and CTGF

H Ihn

CURRENT OPINION IN RHEUMATOLOGY (2002)