4.6 Article

Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

DNA methylation-based classification of central nervous system tumours

David Capper et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer

Jacqulyne P. Robichaux et al.

NATURE MEDICINE (2018)

Article Multidisciplinary Sciences

Altered conformational landscape and dimerization dependency underpins the activation of EGFR by αC-β4 loop insertion mutations

Zheng Ruan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Clinical Neurology

Bithalamic gliomas may be molecularly distinct from their unilateral high-grade counterparts

Alberto Broniscer et al.

BRAIN PATHOLOGY (2018)

Article Clinical Neurology

Pediatric thalamic tumors in the MRI era: a Canadian perspective

Paul Steinbok et al.

CHILDS NERVOUS SYSTEM (2016)

Article Clinical Neurology

Neuropsychological Deterioration Predicts Tumor Progression in a Young Boy With Bithalamic Glioma

Laura Peruzzi et al.

APPLIED NEUROPSYCHOLOGY-CHILD (2016)

Article Pathology

EGFR Exon 20 Insertion/Duplication Mutations Characterize Fibrous Hamartoma of Infancy

Jason Y. Park et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2016)

Article Medicine, General & Internal

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

Daniel J. Brat et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Multidisciplinary Sciences

Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

David A. Nathanson et al.

SCIENCE (2014)

Article Clinical Neurology

Pediatric bilateral large concurrent thalamic glioblastoma: An unusual case report

Nityanand Pandey et al.

JOURNAL OF PEDIATRIC NEUROSCIENCES (2014)

Article Biotechnology & Applied Microbiology

Functional normalization of 450k methylation array data improves replication in large cancer studies

Jean-Philippe Fortin et al.

GENOME BIOLOGY (2014)

Article Biochemistry & Molecular Biology

The Somatic Genomic Landscape of Glioblastoma

Cameron W. Brennan et al.

Editorial Material Clinical Neurology

Bilateral Thalamic Lesions in a Child

Puneet Jain et al.

EUROPEAN NEUROLOGY (2013)

Article Oncology

Natural History and Molecular Characteristics of Lung Cancers Harboring EGFR Exon 20 Insertions

Geoffrey R. Oxnard et al.

JOURNAL OF THORACIC ONCOLOGY (2013)

Article Biochemistry & Molecular Biology

Low-level processing of Illumina Infinium DNA Methylation BeadArrays

Timothy J. Triche et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Clinical Neurology

Bilateral thalamic glioma in a 6-year-old child

Dinesh K. Rajput et al.

JOURNAL OF PEDIATRIC NEUROSCIENCES (2010)

Article Medicine, General & Internal

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors

IK Mellinghoff et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Clinical Neurology

Diagnostic difficulties in childhood bilateral thalamic astrocytomas

S Gudowius et al.

NEUROPEDIATRICS (2002)

Article Clinical Neurology

Bilateral thalamic tumors in children

C Di Rocco et al.

CHILDS NERVOUS SYSTEM (2002)