4.7 Review

Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls

Mads E. Hauberg et al.

MOLECULAR PSYCHIATRY (2019)

Article Biochemistry & Molecular Biology

Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly

Sreejith J. Nair et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)

Article Cell Biology

The RNA N6-methyladenosine modification landscape of human fetal tissues

Shan Xiao et al.

NATURE CELL BIOLOGY (2019)

Article Multidisciplinary Sciences

Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties

Steven Boeynaems et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

m6A enhances the phase separation potential of mRNA

Ryan J. Ries et al.

NATURE (2019)

Article Multidisciplinary Sciences

C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution

Tsukasa Kouno et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

Antonio Pezone et al.

SCIENTIFIC REPORTS (2019)

Article Biochemistry & Molecular Biology

Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs

Katsutoshi Imamura et al.

EMBO JOURNAL (2018)

Article Cell Biology

Widespread transcriptional pausing and elongation control at enhancers

Telmo Henriques et al.

GENES & DEVELOPMENT (2018)

Article Immunology

Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation

Xiang Xiao et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

Article Biochemistry & Molecular Biology

MUNC, an Enhancer RNA Upstream from the MYOD Gene, Induces a Subgroup of Myogenic Transcripts in trans Independently of MyoD

Magdalena A. Cichewicz et al.

MOLECULAR AND CELLULAR BIOLOGY (2018)

Article Biochemistry & Molecular Biology

A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans

Pei-Fang Tsai et al.

MOLECULAR CELL (2018)

Article Biochemistry & Molecular Biology

Targeted Enhancer Activation by a Subunit of the Integrator Complex

Elisa Barbieri et al.

MOLECULAR CELL (2018)

Article Multidisciplinary Sciences

RNA buffers the phase separation behavior of prion-like RNA binding proteins

Shovamayee Maharana et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

mRNA structure determines specificity of a polyQ-driven phase separation

Erin M. Langdon et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Coactivator condensation at super-enhancers links phase separation and gene control

Benjamin R. Sabari et al.

SCIENCE (2018)

Review Biochemistry & Molecular Biology

Paraspeckles: Where Long Noncoding RNA Meets Phase Separation

Archa H. Fox et al.

TRENDS IN BIOCHEMICAL SCIENCES (2018)

Article Multidisciplinary Sciences

Dissecting super-enhancer hierarchy based on chromatin interactions

Jialiang Huang et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program

Yuliang Tan et al.

MOLECULAR CELL (2018)

Article Biochemistry & Molecular Biology

RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation

Homa Rahnamoun et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Multidisciplinary Sciences

Transcription factor dimerization activates the p300 acetyltransferase

Esther Ortega et al.

NATURE (2018)

Article Immunology

Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells

Charles F. Spurlock et al.

JOURNAL OF IMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines

Xueyin Wang et al.

MOLECULAR CELL (2017)

Article Biochemistry & Molecular Biology

Intragenic Enhancers Attenuate Host Gene Expression

Senthilkumar Cinghu et al.

MOLECULAR CELL (2017)

Article Biochemistry & Molecular Biology

SERPINB2 is regulated by dynamic interactions with pause-release proteins and enhancer RNAs

Lihua Shii et al.

MOLECULAR IMMUNOLOGY (2017)

Review Cell Biology

Biomolecular condensates: organizers of cellular biochemistry

Salman F. Banani et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Article Genetics & Heredity

Genome-wide profiling of transcribed enhancers during macrophage activation

Elena Denisenko et al.

EPIGENETICS & CHROMATIN (2017)

Article Multidisciplinary Sciences

Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature

Stephanie Le Gras et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

RNA Binding to CBP Stimulates Histone Acetylation and Transcription

Daniel A. Bose et al.

Article Biochemistry & Molecular Biology

Compositional Control of Phase-Separated Cellular Bodies

Salman F. Banani et al.

Review Biochemistry & Molecular Biology

Chromatin remodeling effects on enhancer activity

Estela Garcia-Gonzalez et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Article Biochemistry & Molecular Biology

The interaction of PRC2 with RNA or chromatin is mutually antagonistic

Manuel Beltran et al.

GENOME RESEARCH (2016)

Article Biochemistry & Molecular Biology

Unlinking an lncRNA from Its Associated cis Element

Vikram R. Paralkar et al.

MOLECULAR CELL (2016)

Article Genetics & Heredity

Hierarchy within the mammary STAT5-driven Wap super-enhancer

Ha Youn Shin et al.

NATURE GENETICS (2016)

Review Genetics & Heredity

Enhancers as non-coding RNA transcription units: recent insights and future perspectives

Wenbo Li et al.

NATURE REVIEWS GENETICS (2016)

Article Multidisciplinary Sciences

Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation

Jun Liang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Biochemistry & Molecular Biology

Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus

Yea Woon Kim et al.

BIOSCIENCE REPORTS (2015)

Article Biotechnology & Applied Microbiology

High-density P300 enhancers control cell state transitions

Steven Witte et al.

BMC GENOMICS (2015)

Article Biochemistry & Molecular Biology

RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer Activity

Evangelos Pefanis et al.

Article Cardiac & Cardiovascular Systems

CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis

Samir Ounzain et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)

Article Biochemistry & Molecular Biology

Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination

Liv M. I. Austenaa et al.

MOLECULAR CELL (2015)

Article Biochemistry & Molecular Biology

RNA Controls PolyQ Protein Phase Transitions

Huaiying Zhang et al.

MOLECULAR CELL (2015)

Article Biochemistry & Molecular Biology

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

Yuan Lin et al.

MOLECULAR CELL (2015)

Article Biochemistry & Molecular Biology

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

Timothy J. Nott et al.

MOLECULAR CELL (2015)

Article Multidisciplinary Sciences

Integrator mediates the biogenesis of enhancer RNAs

Fan Lai et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

The histone variant H2A.Z is an important regulator of enhancer activity

Nylene Brunelle et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Multidisciplinary Sciences

New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors

Christopher Benner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

RNA transcribed from a distal enhancer is required for activating the chromatin at the promoter of the gonadotropin α-subunit gene

Lilach Pnueli et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs

Nasun Hah et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Transcription factor trapping by RNA in gene regulatory elements

Alla A. Sigova et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

Genetic and epigenetic fine mapping of causal autoimmune disease variants

Kyle Kai-How Farh et al.

NATURE (2015)

Article Multidisciplinary Sciences

Genome-wide analysis of enhancer RNA in gene regulation across 12 mouse tissues

Jen-Hao Cheng et al.

SCIENTIFIC REPORTS (2015)

Article Biochemistry & Molecular Biology

Enhancer Activation Requires trans-Recruitment of a Mega Transcription Factor Complex

Zhijie Liu et al.

Article Biochemistry & Molecular Biology

Regulatory Interactions between RNA and Polycomb Repressive Complex 2

Catherine Cifuentes-Rojas et al.

MOLECULAR CELL (2014)

Article Biochemistry & Molecular Biology

Integrator Regulates Transcriptional Initiation and Pause Release following Activation

Alessandro Gardini et al.

MOLECULAR CELL (2014)

Article Biochemistry & Molecular Biology

Enhancer RNA Facilitates NELF Release from Immediate Early Genes

Katie Schaukowitch et al.

MOLECULAR CELL (2014)

Article Multidisciplinary Sciences

An atlas of active enhancers across human cell types and tissues

Robin Andersson et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones

Tomohiko Kanno et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)

Article Multidisciplinary Sciences

Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation

Chen-Lin Hsieh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Cell Biology

In search of the determinants of enhancer-promoter interaction specificity

Joris van Arensbergen et al.

TRENDS IN CELL BIOLOGY (2014)

Article Multidisciplinary Sciences

Nuclear stability and transcriptional directionality separate functionally distinct RNA species

Robin Andersson et al.

NATURE COMMUNICATIONS (2014)

Article Genetics & Heredity

Tissue-Specific RNA Expression Marks Distant-Acting Developmental Enhancers

Han Wu et al.

PLOS GENETICS (2014)

Article Biochemistry & Molecular Biology

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte et al.

Article Biochemistry & Molecular Biology

Super-Enhancers in the Control of Cell Identity and Disease

Denes Hnisz et al.

Article Biochemistry & Molecular Biology

Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions

Kirthi Pulakanti et al.

EPIGENETICS (2013)

Article Biochemistry & Molecular Biology

Enhancer transcripts mark active estrogen receptor binding sites

Nasun Hah et al.

GENOME RESEARCH (2013)

Article Biochemistry & Molecular Biology

eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription

Carlos A. Melo et al.

MOLECULAR CELL (2013)

Article Biochemistry & Molecular Biology

eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci

Kambiz Mousavi et al.

MOLECULAR CELL (2013)

Article Biochemistry & Molecular Biology

Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription

Minna U. Kaikkonen et al.

MOLECULAR CELL (2013)

Article Multidisciplinary Sciences

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Michael T. Y. Lam et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

Syuzo Kaneko et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality

Evgenia Ntini et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

Article Multidisciplinary Sciences

The long-range interaction landscape of gene promoters

Amartya Sanyal et al.

NATURE (2012)

Article Multidisciplinary Sciences

Landscape of transcription in human cells

Sarah Djebali et al.

NATURE (2012)

Article Multidisciplinary Sciences

DNA-binding factors shape the mouse methylome at distal regulatory regions

Michael B. Stadler et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters

Frederic Koch et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Multidisciplinary Sciences

Widespread transcription at neuronal activity-regulated enhancers

Tae-Kyung Kim et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

Francesca De Santa et al.

PLOS BIOLOGY (2010)

Article Multidisciplinary Sciences

Role of histone H3 lysine 27 methylation in polycomb-group silencing

R Cao et al.

SCIENCE (2002)