Journal
CARBOHYDRATE POLYMERS
Volume 150, Issue -, Pages 330-352Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2016.05.029
Keywords
Bacterial cellulose; Bioengineering; Biomedical application; Composites; Nanocellulose
Categories
Funding
- Academy of Finland [252215, 281300]
- University of Helsinki
- Biocentrum Helsinki
- European Research Council [310892]
- Higher Education Commission of Pakistan
- Academy of Finland (AKA) [281300, 281300] Funding Source: Academy of Finland (AKA)
- European Research Council (ERC) [310892] Funding Source: European Research Council (ERC)
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Bacterial cellulose (BC) synthesized by certain species of bacteria, is a fascinating biopolymer with unique physical and mechanical properties. BC's applications range from traditional dessert, gelling, stabilizing and thickening agent in the food industry to advanced high-tech applications, such as immobilization of enzymes, bacteria and fungi, tissue engineering, heart valve prosthesis, artificial blood vessels, bone, cartilage, cornea and skin, and dental root treatment. Various BC -composites have been designed and investigated in order to enhance its biological applicability. This review focuses on the application of BC-based composites for microbial control, wound dressing, cardiovascular, ophthalmic, skeletal, and endodontics systems. Moreover, applications in controlled drug delivery, biosensors/bioanalysis, immobilization of enzymes and cells, stem cell therapy and skin tissue repair are also highlighted. This review will provide new insights for academia and industry to further assess the BC-based composites in terms of practical applications and future commercialization for biomedical and pharmaceutical purposes. (C) 2016 Elsevier Ltd. All rights reserved.
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