Journal
REGENERATIVE THERAPY
Volume 11, Issue -, Pages 75-80Publisher
ELSEVIER
DOI: 10.1016/j.reth.2019.05.006
Keywords
Spinal cord injury; Neural precursor cells; Induced pluripotent stem cells; Clinical application
Categories
Funding
- Research Center Network for the Realization of Regenerative Medicine
- Japan Agency for Medical Research and Development (AMED) [18bk0104050h0003]
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For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications. (C) 2019, The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V.
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