Journal
BIOTECHNOLOGY ADVANCES
Volume 33, Issue 1, Pages 117-123Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2014.11.012
Keywords
Ricin; Bioterrorism; Detection methods; Plant toxins
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Funding
- US Food and Drug Administration (FDA) Medical Countermeasure Initiatives
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Ricin is a plant toxin with high bioterrorism potential due to its natural abundance and potency in inducing cell death. Early detection of the active toxin is essential for developing appropriate countermeasures. Here we review concepts for designing ricin detection methods, including mechanism of action of the toxin, advantages and disadvantages of current detection assays, and perspectives on the future development of rapid and reliable methods for detecting ricin in environmental samples. Published by Elsevier Inc.
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