Related references
Note: Only part of the references are listed.Relevance of Half-Life in Drug Design
Dennis A. Smith et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Dietary tryptophan alleviates dextran sodium sulfate-induced colitis through aryl hydrocarbon receptor in mice
Jahidul Islam et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2017)
Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease
Ryuichi Okamoto et al.
JOURNAL OF GASTROENTEROLOGY (2016)
CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
Bruno Lamas et al.
NATURE MEDICINE (2016)
AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice
Jeremy A. Goettel et al.
CELL REPORTS (2016)
Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage
Xinyang Song et al.
IMMUNITY (2015)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Jimmy Z. Liu et al.
NATURE GENETICS (2015)
Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective
Anna Kaplan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells
Jie Cheng et al.
NATURE COMMUNICATIONS (2015)
Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation
Troy D. Hubbard et al.
DRUG METABOLISM AND DISPOSITION (2015)
Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen
Tu Anh N. Pham et al.
CELL HOST & MICROBE (2014)
PLUMED 2: New feathers for an old bird
Gareth A. Tribello et al.
COMPUTER PHYSICS COMMUNICATIONS (2014)
The role of ligand efficiency metrics in drug discovery
Andrew L. Hopkins et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Innate lymphoid cells regulate intestinal epithelial cell glycosylation
Yoshiyuki Goto et al.
SCIENCE (2014)
IL-17A but not IL-22 suppresses the replication of hepatitis B virus mediated by over-expression of MxA and OAS mRNA in the HepG2.2.15 cell line
Bing Wang et al.
ANTIVIRAL RESEARCH (2013)
Nongenotoxic Carcinogenicity of Chemicals: Mechanisms of Action and Early Recognition through a New Set of Structural Alerts
Romualdo Benigni et al.
CHEMICAL REVIEWS (2013)
Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22
Teresa Zelante et al.
IMMUNITY (2013)
Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora
Ju Qiu et al.
IMMUNITY (2013)
Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation
Lisa A. Mielke et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A Domain
Dalei Wu et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Role of the gut microbiota in immunity and inflammatory disease
Nobuhiko Kamada et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
Wolfgang Hueber et al.
GUT (2012)
The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells
Ju Qiu et al.
IMMUNITY (2012)
Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation
Ying Li Silvia Innocentin et al.
CELL (2011)
Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract
Ivan Monteleone et al.
GASTROENTEROLOGY (2011)
New Aryl Hydrocarbon Receptor Homology Model Targeted To Improve Docking Reliability
Ilaria Motto et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles
Elina A. Kiss et al.
SCIENCE (2011)
Open Babel: An open chemical toolbox
Noel M. O'Boyle et al.
JOURNAL OF CHEMINFORMATICS (2011)
Software News and Update AutoDock Vina: Improving the Speed and Accuracy of Docking with a New Scoring Function, Efficient Optimization, and Multithreading
Oleg Trott et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
Dermot P. B. McGovern et al.
NATURE GENETICS (2010)
Detection of the TCDD Binding-Fingerprint within the Ah Receptor Ligand Binding Domain by Structurally Driven Mutagenesis and Functional Analysis
Alessandro Pandini et al.
BIOCHEMISTRY (2009)
The Suggested Physiologic Aryl Hydrocarbon Receptor Activator and Cytochrome P4501 Substrate 6-Formylindolo[3,2-b]carbazole Is Present in Humans
Emma Wincent et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands
William H. Bisson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells
Sara Trifari et al.
NATURE IMMUNOLOGY (2009)
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin a generation in the gut
Masayuki Tsuji et al.
IMMUNITY (2008)
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
Marc Veldhoen et al.
NATURE (2008)
AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell lines
Sarah L. Hockley et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2007)
Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis
Alessandro Pandini et al.
BIOCHEMISTRY (2007)
Statistical potential for assessment and prediction of protein structures
Min-Yi Shen et al.
PROTEIN SCIENCE (2006)
Alterations in intestinal fatty acid metabolism in inflammatory bowel disease
S Heimerl et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Increased expression of interleukin 17 in inflammatory bowel disease
S Fujino et al.
GUT (2003)
Half-lives of tetra-, penta-, hexa-, hepta-, and octachlorodibenzo-p-dioxin in rats, monkeys, and humans -: a critical review
HJ Geyer et al.
CHEMOSPHERE (2002)