Journal
NATURE REVIEWS MATERIALS
Volume 5, Issue 2, Pages 149-165Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41578-019-0167-3
Keywords
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Funding
- Center for Advanced Soft Electronics (Global Frontier Project) [CASE-2015M3A6A5072945]
- Engineering Research Center (ERC) Program [NRF-2017R1A5A1014708]
- National Research Foundation (NRF) - Ministry of Science and ICT, Korea [2017R1E1A1A03070458]
- Stanford Catalyst for Collaborative Solutions Program
- Stanford Bio-X seed funding
- Department of Defense Air Force Office of Scientific Research [FA9550-15-1-0106]
- Samsung Electronics
- Korea Technology & Information Promotion Agency for SMEs (TIPA) [S2482887] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [2017R1E1A1A03070458] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Numerous light-based diagnostic and therapeutic devices are routinely used in the clinic. These devices have a familiar look as items plugged in the wall or placed at patients' bedsides, but recently, many new ideas have been proposed for the realization of implantable or wearable functional devices. Many advances are being fuelled by the development of multifunctional materials for photonic healthcare devices. However, the finite depth of light penetration in the body is still a serious constraint for their clinical applications. In this Review, we discuss the basic concepts and some examples of state-of-the-art implantable and wearable photonic healthcare devices for diagnostic and therapeutic applications. First, we describe emerging multifunctional materials critical to the advent of next-generation implantable and wearable photonic healthcare devices and discuss the path for their clinical translation. Then, we examine implantable photonic healthcare devices in terms of their properties and diagnostic and therapeutic functions. We next describe exemplary cases of noninvasive, wearable photonic healthcare devices across different anatomical applications. Finally, we discuss the future research directions for the field, in particular regarding mobile healthcare and personalized medicine. Multifunctional materials are critical to enable next-generation implantable and wearable photonic healthcare devices. This Review examines these emerging materials and discusses the path for their clinical translation, along with the future research directions for the field, particularly regarding mobile healthcare and personalized medicine.
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