Related references
Note: Only part of the references are listed.Hypoxia regulates angeogenic-osteogenic coupling process via up-regulating IL-6 and IL-8 in human osteoblastic cells through hypoxia-inducible factor 1 alpha pathway
Xiulong Niu et al.
CYTOKINE (2019)
9za plays cytotoxic and proapoptotic roles and induces cytoprotective autophagy through the PDK1/Akt/mTOR axis in non-small-cell lung cancer
Rangru Liu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Ponatinib Inhibits Proliferation and Induces Apoptosis of Liver Cancer Cells, but Its Efficacy Is Compromised by Its Activation on PDK1/Akt/mTOR Signaling
Chang Liu et al.
MOLECULES (2019)
Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity
Johannes Vogel et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Autophagy activation facilitates mechanical stimulation-promoted osteoblast differentiation and ameliorates hindlimb unloading-induced bone loss
Zezhu Zhou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Reversal of the Warburg effect with DCA in PDGF-treated human PASMC is potentiated by pyruvate dehydrogenase kinase-1 inhibition mediated through blocking Akt/GSK-3β signalling
Bingbing Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
Hypoxic Microenvironment and Metastatic Bone Disease
Toru Hiraga
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway
Fei Han et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2017)
LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway
Chao Zhu et al.
CELLULAR SIGNALLING (2016)
The PI3K/AKT cell signaling pathway is involved in regulation of osteoporosis
Jian-Cheng Xi et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2015)
Up-regulation of glycolytic metabolism is required for HIF1α-driven bone formation
Jenna N. Regan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Glucocorticoids and bone: local effects and systemic implications
Holger Henneicke et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Hydrogen peroxide sensing, signaling and regulation of transcription factors
H. Susana Marinho et al.
REDOX BIOLOGY (2014)
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
Gregg L. Semenza
Annual Review of Pathology-Mechanisms of Disease (2013)
Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
Michael H. Rabinowitz
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation
J. Li et al.
CELL DEATH & DISEASE (2013)
The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO
Erinn B. Rankin et al.
CELL (2012)
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
Gregg L. Semenza
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Hypoxia Inhibits Osteogenesis in Human Mesenchymal Stem Cells through Direct Regulation of RUNX2 by TWIST
Der-Chih Yang et al.
PLOS ONE (2011)
Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
Robert S. Weinstein et al.
AGING CELL (2010)
Role of HIF-1 alpha in skeletal development
Chao Wan et al.
SKELETAL BIOLOGY AND MEDICINE (2010)
Glucocorticoids Suppress Bone Formation by Attenuating Osteoblast Differentiation via the Monomeric Glucocorticoid Receptor
Alexander Rauch et al.
CELL METABOLISM (2010)
Glucocorticoid-Induced Autophagy in Osteocytes
Xuechun Xia et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Hypoxia Induces BMP-2 Expression Via ILK, Akt, mTOR, and HIF-1 Pathways in Osteoblasts
Wen-Pei Tseng et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells
Long Chen et al.
LABORATORY INVESTIGATION (2010)
Management of glucocorticoid-induced osteoporosis
Juliet Compston
NATURE REVIEWS RHEUMATOLOGY (2010)
ACTH protects against glucocorticoid-induced osteonecrosis of bone
Mone Zaidi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Down-Regulation of 3-Phosphoinositide-Dependent Protein Kinase-1 Levels Inhibits Migration and Experimental Metastasis of Human Breast Cancer Cells
Ying Liu et al.
MOLECULAR CANCER RESEARCH (2009)
The role of glucocorticoids and progestins in inflammatory, autoimmune, and infectious disease
A. Sasha Tait et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration
Chao Wan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Glucocorticoid receptor physiology
Marjet D. Heitzer et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2007)
Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth
Alice Fiona Ford-Hutchinson et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2007)
Essential role of PDK1 in regulating endothelial cell migration
Luca Primo et al.
JOURNAL OF CELL BIOLOGY (2007)
The hypoxia-inducible factor a pathway couples angiogenesis to osteogenesis during skeletal development
Ying Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Hypoxia-inducible factor-1 (HIF-1)
Qingdong Ke et al.
MOLECULAR PHARMACOLOGY (2006)
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
I Papandreou et al.
CELL METABOLISM (2006)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
Hypoxia-inducible factor (HIF-1)α:: its protein stability and biological functions
JW Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2004)
Glucocorticoid-induced osteopenia in the mouse as assessed by histomorphometry, microcomputed tomography, and biochemical markers
F McLaughlin et al.
BONE (2002)
Share Paper
