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PLoS One (2013)
Sialic Acid Linkage in Glycosphingolipids Is a Molecular Correlate for Trafficking and Delivery of Extracellular Cargo
Madhu Sudhan Ravindran et al.
TRAFFIC (2013)
Effects of Tryptophan Content and Backbone Spacing on the Uptake Efficiency of Cell-Penetrating Peptides
Hanna A. Rydberg et al.
BIOCHEMISTRY (2012)
Membrane interactions of two arginine-rich peptides with different cell internalization capacities
Astrid Walrant et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans
Helene L. Amand et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
Inhibition of Aggregation of Amyloid β42 by Arginine-Containing Small Compounds
Takayasu Kawasaki et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2012)
The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis
Thorsten R. Doeppner et al.
BRAIN (2012)
Early ghrelin treatment attenuates disruption of the blood brain barrier and apoptosis after traumatic brain injury through a UCP-2 mechanism
N. E. Lopez et al.
BRAIN RESEARCH (2012)
NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS
Eugenia Cifuentes-Pagano et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
A comprehensive summary of LL-37, the factotum human cathelicidin peptide
Dieter Vandamme et al.
CELLULAR IMMUNOLOGY (2012)
Heterodimerization of human apelin and kappa opioid receptors: Roles in signal transduction
Yalin Li et al.
CELLULAR SIGNALLING (2012)
Disruption of NMDAR-CRMP-2 signaling protects against focal cerebral ischemic damage in the rat middle cerebral artery occlusion model
Joel M. Brittain et al.
CHANNELS (2012)
The role of endothelial cell adhesion molecules P-selectin, E-selectin and intercellular adhesion molecule-1 in leucocyte recruitment induced by exogenous methylglyoxal
Yang Su et al.
IMMUNOLOGY (2012)
Apelin-13 Protects the Brain Against Ischemic Reperfusion Injury and Cerebral Edema in a Transient Model of Focal Cerebral Ischemia
Mehdi Khaksari et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2012)
Multimodal Neuroprotection Induced by PACAP38 in Oxygen-Glucose Deprivation and Middle Cerebral Artery Occlusion Stroke Models
Philip Lazarovici et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2012)
Administration of COG1410 Reduces Axonal Amyloid Precursor Protein Immunoreactivity and Microglial Activation after Controlled Cortical Impact in Mice
Yong Jiang et al.
JOURNAL OF NEUROTRAUMA (2012)
Exogenous Administration of PACAP Alleviates Traumatic Brain Injury in Rats through a Mechanism Involving the TLR4/MyD88/NF-κB Pathway
Shan-Shan Mao et al.
JOURNAL OF NEUROTRAUMA (2012)
Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial
Michael D. Hill et al.
LANCET NEUROLOGY (2012)
CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy
Andrew D. Piekarz et al.
MOLECULAR PAIN (2012)
Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain
Douglas J. Cook et al.
NATURE (2012)
Arginine-Based Inhibitors of Nitric Oxide Synthase: Therapeutic Potential and Challenges
Jan Vitecek et al.
MEDIATORS OF INFLAMMATION (2012)
Specific inhibition of the JNK pathway promotes locomotor recovery and neuroprotection after mouse spinal cord injury
Mariaelena Repici et al.
NEUROBIOLOGY OF DISEASE (2012)
The apoE-mimetic Peptide, COG1410, Improves Functional Recovery in a Murine Model of Intracerebral Hemorrhage
Daniel T. Laskowitz et al.
NEUROCRITICAL CARE (2012)
Critical Role of NADPH Oxidase in Neuronal Oxidative Damage and Microglia Activation following Traumatic Brain Injury
Quan-Guang Zhang et al.
PLOS ONE (2012)
A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage
Anders Bach et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction
Richard Steel et al.
ACS MEDICINAL CHEMISTRY LETTERS (2012)
A PEPTIDE UNCOUPLING CRMP-2 FROM THE PRESYNAPTIC CA2+ CHANNEL COMPLEX DEMONSTRATES EFFICACY IN ANIMAL MODELS OF MIGRAINE AND AIDS THERAPY-INDUCED NEUROPATHY
Matthew S. Ripsch et al.
TRANSLATIONAL NEUROSCIENCE (2012)
Arginine Attenuates Methylglyoxal- and High Glucose-Induced Endothelial Dysfunction and Oxidative Stress by an Endothelial Nitric-Oxide Synthase-Independent Mechanism
Indu Dhar et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
A novel strategy to activate cytoprotective genes in the injured brain
Jing Zhao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Peptide-Glycosaminoglycan Cluster Formation Involving Cell Penetrating Peptides
Anthony Rullo et al.
BIOPOLYMERS (2011)
Identification of Novel Short Peptide Inhibitors of Soluble 37/48 kDa Oligomers of Amyloid β42
Takayasu Kawasaki et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2011)
The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains
Frances Corrigan et al.
BRAIN RESEARCH (2011)
FurinDB: A Database of 20-Residue Furin Cleavage Site Motifs, Substrates and Their Associated Drugs
Sun Tian et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2011)
Attenuation of Neuronal Death by Peptide Inhibitors of AP-1 Activation in Acute and Delayed In Vitro Ischaemia (Oxygen/Glucose Deprivation) Models
Amanda J. Craig et al.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2011)
The Apolipoprotein E-Mimetic Peptide COG112 Inhibits NF-κB Signaling, Proinflammatory Cytokine Expression, and Disease Activity in Murine Models of Colitis
Kshipra Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Neuroprotection against Traumatic Brain Injury by a Peptide Derived from the Collapsin Response Mediator Protein 2 (CRMP2)
Joel M. Brittain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
c-Jun N-terminal Kinase Regulates Soluble Aβ Oligomers and Cognitive Impairment in AD Mouse Model
Alessandra Sclip et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Proteomic analysis of cPKCβII-interacting proteins involved in HPC-induced neuroprotection against cerebral ischemia of mice
Xiangning Bu et al.
JOURNAL OF NEUROCHEMISTRY (2011)
NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injury
Denise R. Cook et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Structures, Biosynthesis, and Functions of Gangliosides-an Overview
Robert K. Yu et al.
JOURNAL OF OLEO SCIENCE (2011)
Excitotoxic neuroprotection and vulnerability with CaMKII inhibition
Nicole M. Ashpole et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
Elucidating the Molecular Basis of Action of a Classic Drug: Guanidine Compounds As Inhibitors of Voltage-Gated Potassium Channels
Jeet Kalia et al.
MOLECULAR PHARMACOLOGY (2011)
Perturbing PSD-95 Interactions With NR2B-subtype Receptors Attenuates Spinal Nociceptive Plasticity and Neuropathic Pain
Richard D'Mello et al.
MOLECULAR THERAPY (2011)
A Cell-penetrating Peptide Suppresses Inflammation by Inhibiting NF-κB Signaling
Yu Fu Wang et al.
MOLECULAR THERAPY (2011)
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex
Joel M. Brittain et al.
NATURE MEDICINE (2011)
A Humanin Derivative Reduces Amyloid Beta Accumulation and Ameliorates Memory Deficit in Triple Transgenic Mice
Takako Niikura et al.
PLOS ONE (2011)
Neuroprotection by Freezing Ischemic Penumbra Evolution Without Cerebral Blood Flow Augmentation With a Postsynaptic Density-95 Protein Inhibitor
Bernt T. Bratane et al.
STROKE (2011)
Bim-Bcl-2 Homology 3 Mimetic Therapy Is Effective at Suppressing Inflammatory Arthritis Through the Activation of Myeloid Cell Apoptosis
John C. Scatizzi et al.
ARTHRITIS AND RHEUMATISM (2010)
Anti-inflammatory and recycling properties of an apolipoprotein mimetic peptide, Ac-hE18A-NH2
Geeta Datta et al.
ATHEROSCLEROSIS (2010)
COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat
Nicholas A. Kaufman et al.
BEHAVIOURAL BRAIN RESEARCH (2010)
Inhibition of the JNK/AP-1 pathway reduces neuronal death and improves behavioral outcome after neonatal hypoxic-ischemic brain injury
Cora H. Nijboer et al.
BRAIN BEHAVIOR AND IMMUNITY (2010)
AP-1 inhibitory peptides attenuate in vitro cortical neuronal cell death induced by kainic acid
Amanda J. Meade et al.
BRAIN RESEARCH (2010)
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner et al.
CELL (2010)
DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke
Weihong Tu et al.
CELL (2010)
c-Jun N-Terminal Kinase Pathway Inhibition in Intracerebral Hemorrhage
Delphine Michel-Monigadon et al.
CEREBROVASCULAR DISEASES (2010)
Nona-D-Arginine Amide Suppresses Corneal Cytokines in Pseudomonas aeruginosa Keratitis
Priyanka Karicherla et al.
CORNEA (2010)
c-Jun N-terminal kinase signaling pathway in excitotoxic cell death following kainic acid-induced status epilepticus
Giada Spigolon et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2010)
Neuroprotective effect of the endogenous neural peptide apelin in cultured mouse cortical neurons
Xiang Jun Zeng et al.
EXPERIMENTAL CELL RESEARCH (2010)
Mitochondria-Targeted Antioxidants Protect Against Amyloid-beta Toxicity in Alzheimer's Disease Neurons
Maria Manczak et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Effective Post-insult Neuroprotection by a Novel Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) Inhibitor
Rebekah S. Vest et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Inhibition of TRPC6 degradation suppresses ischemic brain damage in rats
Wanlu Du et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Role of the c-Jun N-terminal kinase pathway in retinal excitotoxicity, and neuroprotection by its inhibition
Anne-Caroline Bessero et al.
JOURNAL OF NEUROCHEMISTRY (2010)
AP-1 inhibitory peptides are neuroprotective following acute glutamate excitotoxicity in primary cortical neuronal cultures
Amanda J. Meade et al.
JOURNAL OF NEUROCHEMISTRY (2010)
The DREAM Protein Negatively Regulates the NMDA Receptor through Interaction with the NR1 Subunit
Ying Zhang et al.
JOURNAL OF NEUROSCIENCE (2010)
The Anti-Inflammatory and Neuroprotective Effects of Ghrelin in Subarachnoid Hemorrhage-Induced Oxidative Brain Damage in Rats
Mehmet Ersahin et al.
JOURNAL OF NEUROTRAUMA (2010)
Interaction of Arginine with Proteins and the Mechanism by Which It Inhibits Aggregation
Diwakar Shukla et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Small peptide inhibitor of JNKs protects against MPTP-induced nigral dopaminergic injury via inhibiting the JNK-signaling pathway
Jing Pan et al.
LABORATORY INVESTIGATION (2010)
The Pharmacokinetics of Cell-Penetrating Peptides
Dikran Sarko et al.
MOLECULAR PHARMACEUTICS (2010)
Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects
Lin Pei et al.
NATURE MEDICINE (2010)
Novel phage peptides attenuate beta amyloid-42 catalysed hydrogen peroxide production and associated neurotoxicity
K. Taddei et al.
NEUROBIOLOGY OF AGING (2010)
NF-κB inhibition after neonatal cerebral hypoxia-ischemia improves long-term motor and cognitive outcome in rats
Michael A. van der Kooij et al.
NEUROBIOLOGY OF DISEASE (2010)
A CYCLIC PEPTIDE TARGETED AGAINST PSD-95 BLOCKS CENTRAL SENSITIZATION AND ATTENUATES THERMAL HYPERALGESIA
B. W. LeBlanc et al.
NEUROSCIENCE (2010)
THE NEUROPROTECTIVE EFFECTS OF FIBRONECTIN MATS AND FIBRONECTIN PEPTIDES FOLLOWING SPINAL CORD INJURY IN THE RAT
V. R. King et al.
NEUROSCIENCE (2010)
An Apolipoprotein E-Mimetic Stimulates Axonal Regeneration and Remyelination after Peripheral Nerve Injury
Feng-Qiao Li et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Protection of Retinal Ganglion Cells by Caspase Substrate-Binding Peptide IQACRG from N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity
Masaaki Seki et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity
Lichuan Yang et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
TAT-Mediated Protein Transduction of Nogo Extracellular Peptide 1-40 and its Biological Activity
Qiang Wang et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2009)
Neuroprotective Effect of Ghrelin Is Associated with Decreased Expression of Prostate Apoptosis Response-4
Sunyoung Hwang et al.
ENDOCRINE JOURNAL (2009)
The cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activities
Alexander Kloss et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2009)
Neuroprotection against neonatal hypoxia/ischemia-induced cerebral cell death by prevention of calpain-mediated mGluR1 alpha truncation
Miou Zhou et al.
EXPERIMENTAL NEUROLOGY (2009)
Limited role of the c-Jun N-terminal kinase pathway in a neonatal rat model of cerebral hypoxia-ischemia
Vanessa Ginet et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Neuroprotection After Status Epilepticus by Targeting Protein Interactions With Postsynaptic Density Protein 95
Crystal M. Dykstra et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
c-Jun N-Terminal Kinase Pathway Activation in Human and Experimental Cerebral Contusion
Fabrizio Ortolano et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Extrasynaptic NMDA Receptors Couple Preferentially to Excitotoxicity via Calpain-Mediated Cleavage of STEP
Jian Xu et al.
JOURNAL OF NEUROSCIENCE (2009)
Ghrelin Promotes and Protects Nigrostriatal Dopamine Function via a UCP2-Dependent Mitochondrial Mechanism
Zane B. Andrews et al.
JOURNAL OF NEUROSCIENCE (2009)
COG1410, a Novel Apolipoprotein-E Mimetic, Improves Functional and Morphological Recovery in a Rat Model of Focal Brain Ischemia
Elena A. Tukhovskaya et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
COG1410 Improves Cognitive Performance and Reduces Cortical Neuronal Loss in the Traumatically Injured Brain
Michael R. Hoane et al.
JOURNAL OF NEUROTRAUMA (2009)
Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries
Changiz Taghibiglou et al.
NATURE MEDICINE (2009)
Neuroprotection Against Transient Focal Cerebral Ischemia and Oxygen-Glucose Deprivation by Interference with GluR6-PSD95 Protein Interaction
Chang-Zhou Yu et al.
NEUROCHEMICAL RESEARCH (2009)
Unconjugated TAT Carrier Peptide Protects Against Excitotoxicity
Anne Vaslin et al.
NEUROTOXICITY RESEARCH (2009)
Apolipoprotein E-Mimetics Inhibit Neurodegeneration and Restore Cognitive Functions in a Transgenic Drosophila Model of Alzheimer's Disease
Svetlana Sarantseva et al.
PLOS ONE (2009)
Supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice
Ning Xu et al.
PEPTIDES (2009)
Comprehensive proteomic and transcriptomic analysis reveals early induction of a protective anti-oxidative stress response by low-dose proteasome inhibition
Sven Bieler et al.
PROTEOMICS (2009)
Pharmacogenomic Effects of Apolipoprotein E on Intracerebral Hemorrhage
Michael L. James et al.
STROKE (2009)
The Nuclear Factor NF-κB Pathway in Inflammation
Toby Lawrence
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
The design of guanidinium-rich transporters and their internalization mechanisms
Paul A. Wender et al.
ADVANCED DRUG DELIVERY REVIEWS (2008)
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans
Michael Morcos et al.
AGING CELL (2008)
Trans-activator of transcription-mediated delivery of NEP1-40 protein into brain has a neuroprotective effect against focal cerebral ischemic injury via inhibition of neuronal apoptosis
Qiang Wang et al.
ANESTHESIOLOGY (2008)
The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator
Karine Wiegler et al.
CEREBROVASCULAR DISEASES (2008)
Reduction of Alzheimer's Disease Amyloid Plaque Load in Transgenic Mice by D3, a D-Enantiomeric Peptide Identified by Mirror Image Phage Display
Thomas van Groen et al.
CHEMMEDCHEM (2008)
The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-κB activation
Kshipra Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Molecular Basis for Proline- and Arginine-Rich Peptide Inhibition of Proteasome
Asokan Anbanandam et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Agonistic Behavior of PACAP6-38 on Sensory Nerve Terminals and Cytotrophoblast Cells
D. Reglodi et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2008)
Specific Targeting of Pro-Death NMDA Receptor Signals with Differing Reliance on the NR2B PDZ Ligand
Francesc X. Soriano et al.
JOURNAL OF NEUROSCIENCE (2008)
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
Xue Jun Liu et al.
NATURE MEDICINE (2008)
Opioids modulate post-ischemic progression in a rat model of stroke
Tsung-Kuei Kao et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
D-JNKi, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats
E. Esneault et al.
NEUROSCIENCE (2008)
Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat
Hong-Shuo Sun et al.
STROKE (2008)
Neuroprotection by Cell Permeable TAT-mGluR1 Peptide in Ischemia: Synergy between Carrier and Cargo Sequences
Wei Xu et al.
NEUROSCIENTIST (2008)
Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury
Lauren A. O'Donnell et al.
JOURNAL OF NEUROCHEMISTRY (2007)
The antimicrobial peptide PR-39 has a protective effect against HeLa cell apoptosis
Christopher R. Ross et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2007)
COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury
Daniel T. Laskowitz et al.
JOURNAL OF NEUROTRAUMA (2007)
Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase
Peter G. Arthur et al.
JOURNAL OF NEUROCHEMISTRY (2007)
The novel apolipoprotein E-based peptide COG1410 improves sensorimotor performance and reduces injury magnitude following cortical contusion injury
Michael R. Hoane et al.
JOURNAL OF NEUROTRAUMA (2007)
δPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo
Rachel Bright et al.
BRAIN RESEARCH (2007)
Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat
Yi Yang et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Anti-nociceptive and anti-allodynic effects of a high affinity NOP hexapeptide [Ac-RY(3-Cl)YRWR-NH2] (Syn 1020) in rodents
Taline V. Khroyan et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
The taming of the cell penetrating domain ofthe HIV Tat: Myths and realities
Ashok Chauhan et al.
JOURNAL OF CONTROLLED RELEASE (2007)
Calpain-mediated mGluR1α truncation:: A key step in excitotoxicity
Wei Xu et al.
NEURON (2007)
Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons
C. Centeno et al.
CELL DEATH AND DIFFERENTIATION (2007)
Short polybasic peptide sequences are potent inhibitors of PC5/6 and PC7: Use of positional scanning-synthetic peptide combinatorial libraries as a tool for the optimization of inhibitory sequences
Martin Fugere et al.
MOLECULAR PHARMACOLOGY (2007)
The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands
Kerstin Kandler et al.
INTERNATIONAL IMMUNOLOGY (2006)
Humanin is a novel neuroprotective agent against stroke
Xingshun Xu et al.
STROKE (2006)
Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis
Feng-Qiao Li et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Ghrelin inhibits inflammatory pain in rats: Involvement of the opioid system
Valeria Sibilia et al.
NEUROPHARMACOLOGY (2006)
The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments
Bernard Masri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Neuroprotection of Tat-GluR6-9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways
Xiao-Mei Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: Respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance
ZY Zhuang et al.
JOURNAL OF NEUROSCIENCE (2006)
Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence
DS Pei et al.
BRAIN (2006)
A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage
Junling Gao et al.
NEUROCRITICAL CARE (2006)
Neuroprotection against ischemic brain injury by a small peptide inhibitor of c-Jun N-terminal kinase (JNK) via nuclear and non-nuclear pathways
QH Guan et al.
NEUROSCIENCE (2006)
Cell-permeable, mitochondrial-targeted, peptide antioxidants
Hazel H. Szeto
AAPS JOURNAL (2006)
Synthetic fibronectin peptide exerts neuroprotective effects on transient focal brain ischemia in rats
LR Zhao et al.
BRAIN RESEARCH (2005)
Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization
M Fotin-Mleczek et al.
JOURNAL OF CELL SCIENCE (2005)
Intrathecal. administration of a novel apoE-derived therapeutic peptide improves outcome following perinatal hypoxic-ischemic injury
JD McAdoo et al.
NEUROSCIENCE LETTERS (2005)
Design of peptidyl compounds that affect β-amyloid aggregation:: Importance of surface tension and contex
TJ Gibson et al.
BIOCHEMISTRY (2005)
Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway
YQ Gao et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2005)
Arginine-rich anti-vascular endothelial growth factor (anti-VEGF) hexapeptide inhibits collagen-induced arthritis and VEGF-stimulated productions of TNF-α and IL-6 by human monocytes
SA Yoo et al.
JOURNAL OF IMMUNOLOGY (2005)
Role of arginine in the stabilization of proteins against aggregation
BM Baynes et al.
BIOCHEMISTRY (2005)
A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury
JR Lynch et al.
EXPERIMENTAL NEUROLOGY (2005)
Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1 - Impact on the bioactivation of proproteins
S McMahon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PR39 inhibits apoptosis in hypoxic endothelial cells - Role of inhibitor apoptosis protein-2
JP Wu et al.
CIRCULATION (2004)
The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes
DME Bowdish et al.
JOURNAL OF IMMUNOLOGY (2004)
Inhibition of furin by polyarginine-containing peptides - Nanomolar inhibition by NONA-D-arginine
MM Kacprzak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cross-inhibition between furin and lethal factor inhibitors
JR Peinado et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Protein kinase C δ mediates cerebral reperfusion injury in vivo
R Bright et al.
JOURNAL OF NEUROSCIENCE (2004)
D-JNKI1,a cell-penetrating c-Jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia
L Hirt et al.
STROKE (2004)
Neuropeptide PACAP inhibits hypoxic activation of brain microglia: a protective mechanism against microglial neurotoxicity in ischemia
K Suk et al.
BRAIN RESEARCH (2004)
Ubiquitin-proteasome system and proteasome inhibition: New strategies in stroke therapy
C Wojcik et al.
STROKE (2004)
Pituitary adenylate cyclase activating polypeptide protects dopaminergic neurons and improves behavioral deficits in a rat model of Parkinson's disease
D Reglödi et al.
BEHAVIOURAL BRAIN RESEARCH (2004)
APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response
JR Lynch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
L-arginine polymers enhance coronary flow and reduce oxidative stress following cardiac transplantation in rats
MH Kown et al.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2003)
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
T Borsello et al.
NATURE MEDICINE (2003)
Molecular dynamics simulations of pentapeptides at interfaces:: Salt bridge and cation-π interactions
MP Aliste et al.
BIOCHEMISTRY (2003)
Proline- and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity
M Gaczynska et al.
BIOCHEMISTRY (2003)
Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1
NM Zhou et al.
VIROLOGY (2003)
Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts
PJ Thornalley
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Protective effect of apolipoprotein E-mimetic peptides on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cell cultures
M Aono et al.
NEUROSCIENCE (2003)
Effects of pretreatment with PACAP on the infarct size and functional outcome in rat permanent focal cerebral ischemia
D Reglodi et al.
PEPTIDES (2002)
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
M Aarts et al.
SCIENCE (2002)
Arginine-rich molecular transporters for drug delivery: Role of backbone spacing in cellular uptake
JB Rothbard et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
The arginine-rich hexapeptide R4W2 is a stereoselective antagonist at the vanilloid receptor 1:: A Ca2+ imaging study in adult rat dorsal root ganglion neurons
HM Himmel et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Functional and analytical evidence for scavenging of oxygen radicals by L-arginine
A Lass et al.
MOLECULAR PHARMACOLOGY (2002)
Antioxidative and myocardial protective effects of L-arginine in oxygen radical-induced injury of isolated perfused rat hearts
A Suessenbacher et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2002)
Possible existence of common internalization mechanisms among arginine-rich peptides
T Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Direct antioxidant properties of creatine
JM Lawler et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated IκBα degradation
JL Bao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
Safe use of the CXCR4 inhibitor ALX40-4C in humans
BJ Doranz et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2001)
Internalization of HIV-1 Tat requires cell surface heparan sulfate proteoglycans
M Tyagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides
DT Laskowitz et al.
EXPERIMENTAL NEUROLOGY (2001)
Identification of differentially expressed genes in rat hippocampus after transient global cerebral ischemia using subtractive cDNA cloning based on polymerase chain reaction
N Yokota et al.
STROKE (2001)
Polyarginines are potent furin inhibitors
A Cameron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Polyarginine enters cells more efficiently than other polycationic homopolymers
DJ Mitchell et al.
JOURNAL OF PEPTIDE RESEARCH (2000)
Arginine-rich peptides are blockers of VR-1 channels with analgesic activity
R Planells-Cases et al.
FEBS LETTERS (2000)
Inhibition of ubiquitin-proteasome pathway-mediated IκBα degradation by a naturally occurring antibacterial peptide
YH Gao et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Delayed systemic administration of PACAP38 is neuroprotective in transient middle cerebral artery occlusion in the rat
D Reglodi et al.
STROKE (2000)
Arginine-based structures are specific inhibitors of cathepsin C -: Application of peptide combinatorial libraries
M Horn et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
PR39, a peptide regulator of angiogenesis
J Li et al.
NATURE MEDICINE (2000)
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